About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:154546 Chen L, et al., Role of the immune modulator programmed cell death-1 during development and apoptosis of mouse retinal ganglion cells. Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4941-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5706746
Gene symbol: Pou4f1
Gene name: POU domain, class 4, transcription factor 1
Antibody: anti-Brn3a (clone 5A3.2 MAB1585)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A upper: postnatal adult (more )
Note: Double labeled: red - Pou4f1; green - Pdcd1 (assay MGI:5706771).
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 1A upper merge , 1A upper left

Specimen 5A WT: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 5A left

Specimen 5A PD-1-/-: postnatal day 2; Pdcd1tm1.1Shr/Pdcd1tm1.1Shr (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 5A middle 1 Increased expression, compared with the wild-type.

Specimen not shown: postnatal day 4 (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present

Specimen not shown: postnatal day 4; Pdcd1tm1.1Shr/Pdcd1tm1.1Shr (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Increased expression, compared with the wild-type.

Specimen not shown: postnatal day 9 (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present

Specimen not shown: postnatal day 9; Pdcd1tm1.1Shr/Pdcd1tm1.1Shr (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Similar to the wild-type.

Specimen not shown: postnatal adult (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present

Specimen not shown: postnatal adult; Pdcd1tm1.1Shr/Pdcd1tm1.1Shr (more )
Note: Data was shown as quantification figures in 5C.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Similar to the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory