Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Cenputm2.1Tfw
Name:	centromere protein U; targeted mutation 2.1, Tatsuo Fukagawa
MGI ID:	MGI:5705083
Synonyms:	CENP-Uflox
Gene:	Cenpu  Location: Chr8:47005063-47033042 bp, + strand  Genetic Position: Chr8, 26.38 cM, cytoband B2
Alliance:	Cenputm2.1Tfw page

Germline Transmission:	Earliest citation of germline transmission: J:223124
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: The targeted vector inserted a loxP site and FRT-flanked splice acceptor, IRES sequence and beta-geo cassette upstream of exon 4 and inserted a second loxP site downstream of exon 6. Flp-mediated recombination removed the beta-geo cassette. (J:223124)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cenpu Mutation:	19 strains or lines available

Original:	J:223124 Kagawa N, et al., The CENP-O complex requirement varies among different cell types. Chromosome Res. 2014 Sep;22(3):293-303
All:	2 reference(s)