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Gene Expression Data
Assay Details
Assay
Reference: J:210446 Tekko T, et al., Initiation and developmental dynamics of Wfs1 expression in the context of neural differentiation and ER stress in mouse forebrain. Int J Dev Neurosci. 2014 Jun;35:80-8
Assay type: RNA in situ
MGI Accession ID: MGI:5704217
Gene symbol: Wfs1
Gene name: wolframin ER transmembrane glycoprotein
Probe: Wfs1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudate-putamen Present Regionally restricted 1E Expression is in the posterior and medial parts of the caudate putamen.

Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudate-putamen Weak Regionally restricted 1F Expression is in the medial part of the caudate putamen.

Specimen 1G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudate-putamen Present Regionally restricted 1G Expression is in the posterior part of the caudate putamen.
TS23: amygdala Weak Regionally restricted 1G Expression is in the medial amygdaloid nucleus.

Specimen 1H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: amygdala Present Regionally restricted 1H Expression is in the central and medial amygdaloid nucleus.

Specimen 1I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: caudate-putamen Strong 1I
TS26: accumbens nucleus Present 1I
TS26: cerebral cortex Present Regionally restricted 1I Expression is in the allocortex.
TS26: telencephalon septum Present Regionally restricted 1I Expression is in dorsal, ventral and intermediate parts of lateral septal nucleus.
TS26: cortical plate Weak Diffuse 1I
TS26: diencephalon Weak Diffuse 1I
TS26: neocortex Weak Diffuse 1I

Specimen 1J: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: caudate-putamen Present 1J
TS26: diencephalon Present 1J
TS26: amygdala Present Regionally restricted 1J Expression is in the interstitial nucleus of posterior limb of anterior commissure.
TS26: telencephalon septum Present Regionally restricted 1J Expression is in the bed nucleus of stria terminalis.
TS26: cerebral cortex Present Regionally restricted 1J Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS26: entorhinal cortex Present Regionally restricted 1J Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS26: piriform cortex Present Regionally restricted 1J Expression is in layer II.
TS26: cortical plate Weak Diffuse 1J
TS26: neocortex Weak Diffuse 1J
TS26: hippocampus region Weak 1J
TS26: telencephalon Weak Regionally restricted 1J Expression is in the subiculum.

Specimen 1K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: amygdala Strong 1K Expression is stronger laterally.
TS26: caudate-putamen Present 1K
TS26: cerebral cortex Present Regionally restricted 1K Expression is in the allocortex.
TS26: cortical plate Weak Diffuse 1K
TS26: diencephalon Weak Diffuse 1K
TS26: neocortex Weak Diffuse 1K
TS26: hippocampus region Weak 1K
TS26: reticular thalamic nucleus Weak 1K
TS26: telencephalon Weak Regionally restricted 1K Expression is in the subiculum.

Specimen 1L: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: amygdala Strong 1L
TS26: parafascicular nucleus Present 1L
TS26: cerebral cortex Present Regionally restricted 1L Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS26: entorhinal cortex Present Regionally restricted 1L Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS26: piriform cortex Present Regionally restricted 1L Expression is in layer II.
TS26: hypothalamus Present Regionally restricted 1L Expression is in the dorsal premammillary and arcuate nuclei.
TS26: cortical plate Weak Diffuse 1L
TS26: diencephalon Weak Diffuse 1L
TS26: neocortex Weak Diffuse 1L
TS26: hippocampus region Weak 1L
TS26: telencephalon Weak Regionally restricted 1L

Specimen 1M: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Strong Regionally restricted 1M Expression is in the anterior part of the caudate putamen.
TS27: insular cortex Present Regionally restricted 1M Expression is in layers V and II/III.
TS27: cingulate cortex Present Regionally restricted 1M Expression is in layer V.
TS27: primary motor cortex Present Regionally restricted 1M Expression is in layer V.
TS27: cerebral cortex Present Regionally restricted 1M Expression is in layer V in the retrospenial cortex.
TS27: lateral septal nucleus Present Regionally restricted 1M Expression is in the dorsal part of the lateral septal nucleus.
TS27: cortical layer VI Weak 1M

Specimen 1N: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Strong Regionally restricted 1N Expression is in the medial part of the caudate putamen.
TS27: bed nucleus of stria terminalis Strong 1N
TS27: hippocampus CA1 Strong 1N
TS27: hippocampus CA2 Strong 1N
TS27: hippocampus CA3 Strong 1N
TS27: amygdala Strong Regionally restricted 1N Expression is in the interstitial nucleus of posterior limb of anterior commissure.
TS27: cingulate cortex Present Regionally restricted 1N Expression is in layer V.
TS27: primary motor cortex Present Regionally restricted 1N Expression is in layer V.
TS27: cerebral cortex Present Regionally restricted 1N Expression is in layer V in the retrospenial cortex.
TS27: dentate gyrus Weak Regionally restricted 1N Expression is in the upper blade.

Specimen 1O: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Strong 1O
TS27: hippocampus CA2 Strong 1O
TS27: hippocampus CA3 Strong 1O
TS27: caudate-putamen Present 1O
TS27: diencephalon Present 1O
TS27: reticular thalamic nucleus Present 1O
TS27: cingulate cortex Present Regionally restricted 1O Expression is in layer V.
TS27: primary motor cortex Present Regionally restricted 1O Expression is in layer V.
TS27: cerebral cortex Present Regionally restricted 1O Expression is in layer V in the retrospenial cortex.
TS27: dentate gyrus Weak Regionally restricted 1O Expression is in the upper blade.

Specimen 1P: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Strong 1P
TS27: hippocampus CA2 Strong 1P
TS27: hippocampus CA3 Strong 1P
TS27: medial amygdaloid nucleus Strong 1P
TS27: caudate-putamen Present 1P
TS27: diencephalon Present 1P
TS27: dentate gyrus Weak Regionally restricted 1P Expression is in the upper blade.

Specimen 2A: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Strong Regionally restricted 2A Expression is in the anterior part of the caudate putamen.
TS27: corpus striatum Present Regionally restricted 2A Expression is in the ventral striatum.
TS27: cortical layer V Present 2A
TS27: lateral septal nucleus Present Regionally restricted 2A Expression is in the dorsal part of the lateral septal nucleus.
TS27: cortical layer VI Weak 2A

Specimen 2B: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Strong Regionally restricted 2B Expression is in the medial part of the caudate putamen.
TS27: bed nucleus of stria terminalis Strong 2B
TS27: amygdala Strong Regionally restricted 2B Expression is in the interstitial nucleus of posterior limb of anterior commissure.
TS27: cerebral cortex Present 2B Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: entorhinal cortex Present 2B Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: piriform cortex Present Regionally restricted 2B Expression is in layer II.
TS27: cortical layer V Present 2B
TS27: cortical layer VI Weak 2B

Specimen 2C: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Present 2C
TS27: cortical layer V Present 2C
TS27: dentate gyrus Present 2C
TS27: diencephalon Present 2C
TS27: hippocampus CA1 Present 2C
TS27: hippocampus CA2 Present 2C
TS27: hippocampus CA3 Present 2C
TS27: subiculum Present 2C
TS27: cerebral cortex Present Regionally restricted 2C Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: entorhinal cortex Present Regionally restricted 2C Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: piriform cortex Present Regionally restricted 2C Expression is in layer II.
TS27: cortical layer VI Weak 2C

Specimen 2D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: basolateral amygdaloid nucleus Strong Regionally restricted 2D Expression is in posterior divisions.
TS27: basomedial amygdaloid nucleus Strong Regionally restricted 2D Expression is in posterior divisions.
TS27: medial amygdaloid nucleus Strong 2D
TS27: caudate-putamen Present 2D
TS27: dentate gyrus Present 2D
TS27: diencephalon Present 2D
TS27: hippocampus CA1 Present 2D
TS27: hippocampus CA2 Present 2D
TS27: hippocampus CA3 Present 2D
TS27: subiculum Present 2D
TS27: cerebral cortex Present Regionally restricted 2D Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: perirhinal cortex Present Regionally restricted 2D Expression is in layer II/III in ecto-, ento- and perirhinal cortices.
TS27: piriform cortex Present Regionally restricted 2D Expression is in layer II.

Specimen 2E: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 2E Expression is in the anterior part of the caudate putamen.
TS28: corpus striatum Present Regionally restricted 2E Expression is in the ventral striatum.
TS28: cerebral cortex Present Regionally restricted 2E Expression is in layer II/III in the retrospenial cortex.
TS28: auditory cortex Present Regionally restricted 2E Expression is in layer II/III.
TS28: cingulate cortex Present Regionally restricted 2E Expression is in layer II/III.
TS28: primary motor cortex Present Regionally restricted 2E Expression is in layer II/III.
TS28: cortical layer VI Weak 2E

Specimen 2F: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 2F Expression is in the medial part of the caudate putamen.
TS28: hippocampus CA1 Strong 2F
TS28: dentate gyrus Weak 2F
TS28: diencephalon Weak 2F
TS28: hippocampus CA3 Weak 2F
TS28: subiculum Weak 2F

Specimen 2G: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: auditory cortex Present Regionally restricted 2G Expression is in layer II/III.
TS28: cingulate cortex Present Regionally restricted 2G Expression is in layer II/III.
TS28: primary motor cortex Present Regionally restricted 2G Expression is in layer II/III.
TS28: cerebral cortex Present Regionally restricted 2G Expression is in layer II/III in the retrospenial cortex.
TS28: hippocampus CA1 Strong 2G
TS28: dentate gyrus Weak 2G
TS28: diencephalon Weak 2G
TS28: hippocampus CA3 Weak 2G
TS28: subiculum Weak 2G

Specimen 2H: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 2H
TS28: medial amygdaloid nucleus Strong 2H
TS28: basolateral amygdaloid nucleus Strong Regionally restricted 2H Expression is in the posterior regions.
TS28: basomedial amygdaloid nucleus Strong Regionally restricted 2H Expression is in the posterior regions.
TS28: dentate gyrus Weak 2H
TS28: diencephalon Weak 2H
TS28: hippocampus CA3 Weak 2H
TS28: subiculum Weak 2H

Specimen 2I: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 2I Expression is in the anterior part of the caudate putamen.
TS28: corpus striatum Present Regionally restricted 2I Expression is in the ventral striatum.
TS28: cortical layer II Present 2I
TS28: cortical layer III Present 2I
TS28: lateral septal nucleus Present Regionally restricted 2I Expression is in the dorsal part of the lateral septal nucleus.

Specimen 2J: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 2J Expression is in the medial part of the caudate putamen.
TS28: arcuate nucleus Present 2J
TS28: cortical layer II Present 2J
TS28: cortical layer III Present 2J
TS28: paraventricular hypothalamic nucleus Present 2J
TS28: reticular thalamic nucleus Present 2J
TS28: mammillary body Present Regionally restricted 2J Expression is in the dorsal and ventral premammillary nucleus.
TS28: hypothalamus Present Regionally restricted 2J Expression is in the ventromedial hypothalamus.

Specimen 2K: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 2K
TS28: retrohippocampal cortex Strong Regionally restricted 2K Expression is in the parasubiculum.
TS28: arcuate nucleus Present 2K
TS28: cortical layer II Present 2K
TS28: cortical layer III Present 2K
TS28: dorsomedial hypothalamic nucleus Present 2K
TS28: paraventricular hypothalamic nucleus Present 2K
TS28: reticular thalamic nucleus Present 2K
TS28: mammillary body Present Regionally restricted 2K Expression is in the dorsal and ventral premammillary nucleus.
TS28: hypothalamus Present Regionally restricted 2K Expression is in the ventromedial hypothalamus.
TS28: diencephalon Weak 2K

Specimen 2L: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 2L
TS28: retrohippocampal cortex Strong Regionally restricted 2L Expression is in the parasubiculum.
TS28: basolateral amygdaloid nucleus Present Regionally restricted 2L Expression is in posterior regions.
TS28: basomedial amygdaloid nucleus Present Regionally restricted 2L Expression is in posterior regions.
TS28: arcuate nucleus Present 2L
TS28: cortical layer II Present 2L
TS28: cortical layer III Present 2L
TS28: paraventricular hypothalamic nucleus Present 2L
TS28: reticular thalamic nucleus Present 2L
TS28: ventromedial hypothalamic nucleus Present 2L
TS28: mammillary body Present Regionally restricted 2L Expression is in the dorsal and ventral premammillary nucleus.
TS28: hypothalamus Present Regionally restricted 2L Expression is in the ventromedial hypothalamus.
TS28: diencephalon Weak 2L

Specimen 2M: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Trace Regionally restricted 2M Expression is in the anterior part of the caudate putamen.
TS28: cortical layer II Present 2M
TS28: cortical layer III Present 2M
TS28: lateral septal nucleus Present Regionally restricted 2M Expression is in the dorsal part of the lateral septal nucleus.

Specimen 2N: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Trace 2N Expression is in the medial part of the caudate putamen.
TS28: bed nucleus of stria terminalis Present 2N
TS28: cortical layer II Present 2N
TS28: cortical layer III Present 2N
TS28: amygdala Present Regionally restricted 2N Expression is in the interstitial nucleus of posterior limb of anterior commissure.
TS28: brain nucleus Trace 2N

Specimen 2O: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 2O
TS28: retrohippocampal cortex Strong Regionally restricted 2O Expression is in the parasubiculum.
TS28: caudate-putamen Present Regionally restricted 2O Expression is in the posterior part of the caudate putamen.
TS28: cortical layer II Present 2O
TS28: cortical layer III Present 2O
TS28: brain nucleus Trace 2O
TS28: diencephalon Absent 2O

Specimen 2P: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 2P
TS28: retrohippocampal cortex Strong Regionally restricted 2P Expression is in the parasubiculum.
TS28: cortical layer II Present 2P
TS28: cortical layer III Present 2P
TS28: basolateral amygdaloid nucleus Weak 2P
TS28: basomedial amygdaloid nucleus Weak 2P
TS28: diencephalon Absent 2P

Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: neocortex Weak Diffuse 4A

Specimen 4C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cingulate cortex Present Regionally restricted 4C Expression is in layer V.
TS27: primary motor cortex Present Regionally restricted 4C Expression is in layer V.
TS27: cerebral cortex Present Regionally restricted 4C Expression is in layer V in the retrospenial cortex.
TS27: cortical plate Present 4C

Specimen 4E: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cortical layer V Present 4E
TS27: cortical plate Present 4E

Specimen 4G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 4G
TS28: cortical layer III Present 4G

Specimen 4I: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present 4I

Specimen 4K: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 4K
TS28: cortical layer III Present 4K

Specimen 4M: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 4M
TS28: cortical layer III Present 4M

Specimen 5A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: amygdala Weak Regionally restricted 5aA Expression is in the medial amygdaloid nucleus.
TS23: hypothalamus Present Regionally restricted 5aA Expression is in the paraventricular hypothalamic nucleus.

Specimen 5D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: reticular thalamic nucleus Weak 5aD

Specimen 5G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Strong 5aG There is stronger expression in the subicular part.
TS27: diencephalon Present 5aG
TS27: hippocampus CA2 Present 5aG
TS27: reticular thalamic nucleus Present 5aG
TS27: hippocampus CA3 Weak 5aG
TS27: dentate gyrus Weak Regionally restricted 5aG Expression is in the upper blade.

Specimen 5J: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Present 5aJ
TS27: diencephalon Present 5aJ
TS27: hippocampus CA1 Present 5aJ
TS27: hippocampus CA2 Present 5aJ
TS27: hippocampus CA3 Present 5aJ
TS27: subiculum Present 5aJ

Specimen 5M: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 5aM
TS28: diencephalon Weak 5aM
TS28: hippocampus CA3 Trace 5aM
TS28: subiculum Trace 5aM
TS28: dentate gyrus Trace 5aM There is a discrepancy between the text and Table 2a. The text states expression has faded, the table states it is absent.

Specimen 5P: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 5aP
TS28: retrohippocampal cortex Strong Regionally restricted 5aP Expression is in the parasubiculum.
TS28: diencephalon Absent 5aP

Specimen not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory cortex Present Regionally restricted Expression is in the olfactory tubercle.
TS24: amygdala Present Regionally restricted Expression is in the cortical amygdala.
TS24: hypothalamus Present Regionally restricted Expression is in the ventromedial hypothalamus and the ventral premammillary nucleus.
TS24: telencephalon Weak Diffuse Expression is in the allocortex.

Specimen not shown P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dorsomedial hypothalamic nucleus Present

Specimen Table2a E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: amygdala Present Regionally restricted Expression is in the central and medial nucleus.
TS23: corpus striatum Weak Regionally restricted Expression is in the medial and posterior caudate putamen.
TS23: hypothalamus Weak Regionally restricted Expression is in the paraventricular nucleus.
TS23: cerebral cortex Absent
TS23: hippocampus Absent
TS23: telencephalon septum Absent
TS23: thalamus Absent

Specimen Table2a E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Weak Regionally restricted Expression is in the ectorhinal cortex, perirhinal cortex, piriform, and entorhinal cortex.
TS24: corpus striatum Weak Regionally restricted Expression is in the medial, posterior, nucelus accumbens, and olfactory tubercle.
TS24: amygdala Weak Regionally restricted Expression is in the central, cortical, and medial nucleus.
TS24: hypothalamus Weak Regionally restricted Expression is in the paraventricular, ventromedial hypothalamic nucleus nucleus, and ventral premammillary nucleus and diffuse expression elsewhere.
TS24: hippocampus Absent
TS24: telencephalon septum Absent

Specimen Table2a E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: telencephalon septum Present Regionally restricted Expression is in the lateral septal nucleus.
TS26: cerebral cortex Weak Regionally restricted Expression is in the cingulate, retrospenial, motor, soomatosensory, auditory, visual, insular, ectorhinal, perirhinal, entorhinal and piriform cortex.
TS26: caudate-putamen Weak Regionally restricted Expression is stronger in the posterior than the anterior and medial parts.
TS26: corpus striatum Present Regionally restricted Expression is in the olfactory tubercle.
TS26: accumbens nucleus Present
TS26: amygdala Strong Regionally restricted Expression is in the central and medial nucleus, weaker in the stria terminalis and the interstitial nucleus of posterior limb of anterior commisure. Also weak in the basomedial and basolateral nucleus.
TS26: hippocampus Weak
TS26: thalamus Weak Diffuse Expression is diffuse with weak expression in the reticular nucleus.
TS26: hypothalamus Weak Diffuse Weak expression in the paraventricular, ventromedial hypothalamic nucleus nucleus, arcuate, and dorsal and ventral premammillary nucleus.

Specimen Table2a P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: central amygdaloid nucleus Very strong
TS27: medial amygdaloid nucleus Very strong
TS27: accumbens nucleus Strong
TS27: bed nucleus of stria terminalis Strong
TS27: olfactory tubercle Strong
TS27: subiculum Strong
TS27: caudate-putamen Strong Regionally restricted Strong expression in the posterior, weaker in medial and anterior parts.
TS27: mammillary body Strong Regionally restricted Expression is in the ventral premammillary nucleus, weaker in the dorsal premammillary nucleus.
TS27: basomedial amygdaloid nucleus Moderate
TS27: cortical amygdaloid nucleus Moderate
TS27: hippocampus CA1 Moderate
TS27: reticular thalamic nucleus Moderate
TS27: hypothalamus Moderate Diffuse
TS27: thalamus Moderate Diffuse
TS27: arcuate nucleus Weak
TS27: auditory cortex Weak
TS27: basolateral amygdaloid nucleus Weak
TS27: cingulate cortex Weak
TS27: dentate gyrus Weak
TS27: dorsomedial hypothalamic nucleus Weak
TS27: entorhinal cortex Weak
TS27: hippocampus CA3 Weak
TS27: insular cortex Weak
TS27: lateral amygdaloid nucleus Weak
TS27: lateral septal nucleus Weak
TS27: paraventricular hypothalamic nucleus Weak
TS27: perirhinal cortex Weak
TS27: piriform cortex Weak
TS27: primary motor cortex Weak
TS27: primary somatosensory cortex Weak
TS27: ventromedial hypothalamic nucleus Weak
TS27: visual cortex Weak
TS27: telencephalon Weak Regionally restricted Expression is in the retrospenial cortex, ectorhinal cortex, and in the interstitial nucleus of posterior limb of anterior commissure.

Specimen Table2a P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: central amygdaloid nucleus Very strong
TS27: medial amygdaloid nucleus Very strong
TS27: caudate-putamen Very strong Regionally restricted Stongest in the posterior part, weaker medial and anterior.
TS27: basolateral amygdaloid nucleus Very strong Regionally restricted Strongest in the posterior part.
TS27: accumbens nucleus Strong
TS27: bed nucleus of stria terminalis Strong
TS27: hippocampus CA1 Strong
TS27: olfactory tubercle Strong
TS27: reticular thalamic nucleus Strong
TS27: subiculum Strong
TS27: basomedial amygdaloid nucleus Strong Strongest in the posterior part.
TS27: mammillary body Strong Regionally restricted Expression is in the ventral premammillary nucleus, weaker in the dorsal premammillary nucleus.
TS27: cingulate cortex Moderate
TS27: cortical amygdaloid nucleus Moderate
TS27: hippocampus CA3 Moderate
TS27: lateral septal nucleus Moderate
TS27: piriform cortex Moderate
TS27: primary motor cortex Moderate
TS27: thalamus Moderate Diffuse
TS27: telencephalon Present Regionally restricted Expression is in the retrospenial cortex, ectorhinal cortex, and in the interstitial nucleus of posterior limb of anterior commissure.
TS27: arcuate nucleus Weak
TS27: auditory cortex Weak
TS27: dentate gyrus Weak
TS27: dorsomedial hypothalamic nucleus Weak
TS27: entorhinal cortex Weak
TS27: insular cortex Weak
TS27: lateral amygdaloid nucleus Weak
TS27: paraventricular hypothalamic nucleus Weak
TS27: perirhinal cortex Weak
TS27: primary somatosensory cortex Weak
TS27: ventromedial hypothalamic nucleus Weak
TS27: visual cortex Weak
TS27: hypothalamus Weak Diffuse

Specimen Table2a P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Very strong Regionally restricted Stongest in the posterior part, weaker medial and anterior.
TS28: central amygdaloid nucleus Very strong
TS28: hippocampus CA1 Very strong
TS28: medial amygdaloid nucleus Very strong
TS28: subiculum Very strong
TS28: accumbens nucleus Strong
TS28: olfactory tubercle Strong
TS28: basolateral amygdaloid nucleus Strong Regionally restricted Strongest in the posterior part.
TS28: basomedial amygdaloid nucleus Strong Regionally restricted Strongest in the posterior part.
TS28: mammillary body Strong Regionally restricted Expression is in the ventral premammillary nucleus, weaker in the dorsal premammillary nucleus.
TS28: bed nucleus of stria terminalis Moderate
TS28: cingulate cortex Moderate
TS28: cortical amygdaloid nucleus Moderate
TS28: hippocampus CA3 Moderate
TS28: lateral septal nucleus Moderate
TS28: piriform cortex Moderate
TS28: reticular thalamic nucleus Moderate
TS28: telencephalon Present Regionally restricted Expression is in the retrospenial cortex, ectorhinal cortex, and in the interstitial nucleus of posterior limb of anterior commissure.
TS28: arcuate nucleus Weak
TS28: auditory cortex Weak
TS28: dentate gyrus Weak
TS28: dorsomedial hypothalamic nucleus Weak
TS28: entorhinal cortex Weak
TS28: insular cortex Weak
TS28: lateral amygdaloid nucleus Weak
TS28: paraventricular hypothalamic nucleus Weak
TS28: perirhinal cortex Weak
TS28: primary motor cortex Weak
TS28: primary somatosensory cortex Weak
TS28: ventromedial hypothalamic nucleus Weak
TS28: visual cortex Weak
TS28: hypothalamus Weak Diffuse
TS28: thalamus Weak Diffuse

Specimen Table2a P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Very strong Regionally restricted Stongest in the posterior part, weaker medial and anterior.
TS28: accumbens nucleus Very strong
TS28: central amygdaloid nucleus Very strong
TS28: hippocampus CA1 Very strong
TS28: olfactory tubercle Very strong
TS28: subiculum Very strong
TS28: medial amygdaloid nucleus Strong
TS28: basolateral amygdaloid nucleus Strong Strongest in the posterior part.
TS28: arcuate nucleus Moderate
TS28: bed nucleus of stria terminalis Moderate
TS28: cingulate cortex Moderate
TS28: cortical amygdaloid nucleus Moderate
TS28: hippocampus CA3 Moderate
TS28: piriform cortex Moderate
TS28: reticular thalamic nucleus Moderate
TS28: ventromedial hypothalamic nucleus Moderate
TS28: mammillary body Moderate Regionally restricted Expression is in the ventral premammillary nucleus, weaker in the dorsal premammillary nucleus.
TS28: telencephalon Present Regionally restricted Expression is in the retrospenial cortex, ectorhinal cortex, the interstitial nucleus of posterior limb of anterior commissure, and parasubiculum.
TS28: auditory cortex Weak
TS28: basomedial amygdaloid nucleus Weak
TS28: dorsomedial hypothalamic nucleus Weak
TS28: entorhinal cortex Weak
TS28: insular cortex Weak
TS28: lateral amygdaloid nucleus Weak
TS28: lateral septal nucleus Weak
TS28: paraventricular hypothalamic nucleus Weak
TS28: perirhinal cortex Weak
TS28: primary motor cortex Weak
TS28: primary somatosensory cortex Weak
TS28: visual cortex Weak
TS28: hypothalamus Weak Diffuse
TS28: thalamus Weak Diffuse
TS28: dentate gyrus Absent There is a discrepancy between the text and Table 2a. The text states expression has faded, the table states it is absent.

Specimen Table2a P20: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: lateral septal nucleus Very strong Expression is primarily in the dorsal part.
TS28: caudate-putamen Very strong Stongest in the posterior part, weaker medial and anterior.
TS28: accumbens nucleus Very strong
TS28: central amygdaloid nucleus Very strong
TS28: hippocampus CA1 Very strong
TS28: olfactory tubercle Very strong
TS28: auditory cortex Strong
TS28: cingulate cortex Strong
TS28: cortical amygdaloid nucleus Strong
TS28: entorhinal cortex Strong
TS28: insular cortex Strong
TS28: perirhinal cortex Strong
TS28: piriform cortex Strong
TS28: primary motor cortex Strong
TS28: primary somatosensory cortex Strong
TS28: visual cortex Strong
TS28: telencephalon Strong Regionally restricted Expression is in the ectorhinal cortex, in the interstitial nucleus of posterior limb of anterior commissure, and parasubiculum.
TS28: basolateral amygdaloid nucleus Moderate Strongest in the posterior part.
TS28: reticular thalamic nucleus Moderate Strongest in the posterior part.
TS28: ventromedial hypothalamic nucleus Moderate Strongest in the posterior part.
TS28: basomedial amygdaloid nucleus Weak
TS28: bed nucleus of stria terminalis Weak
TS28: dorsomedial hypothalamic nucleus Weak
TS28: hippocampus CA3 Weak
TS28: lateral amygdaloid nucleus Weak
TS28: medial amygdaloid nucleus Weak
TS28: paraventricular hypothalamic nucleus Weak
TS28: subiculum Weak
TS28: mammillary body Weak Regionally restricted Expression is in the ventral and dorsal premammillary nucleus.
TS28: dentate gyrus Absent

Specimen Table2a Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lateral septal nucleus Very strong Regionally restricted Expression is in the dorsal part.
TS28: caudate-putamen Very strong Regionally restricted tongest in the posterior part, weaker medial and absent in the anterior parts.
TS28: accumbens nucleus Very strong
TS28: central amygdaloid nucleus Very strong
TS28: hippocampus CA1 Very strong
TS28: olfactory tubercle Very strong
TS28: cingulate cortex Strong
TS28: cortical amygdaloid nucleus Strong
TS28: entorhinal cortex Strong
TS28: insular cortex Strong
TS28: perirhinal cortex Strong
TS28: telencephalon Strong Regionally restricted Expression is in the ectorhinal cortex, in the interstitial nucleus of posterior limb of anterior commissure, and parasubiculum.
TS28: auditory cortex Moderate
TS28: primary motor cortex Moderate
TS28: primary somatosensory cortex Moderate
TS28: visual cortex Moderate
TS28: basolateral amygdaloid nucleus Moderate Weaker in the posterior part.
TS28: arcuate nucleus Weak
TS28: bed nucleus of stria terminalis Weak
TS28: dorsomedial hypothalamic nucleus Weak
TS28: lateral amygdaloid nucleus Weak
TS28: medial amygdaloid nucleus Weak
TS28: paraventricular hypothalamic nucleus Weak
TS28: reticular thalamic nucleus Weak
TS28: ventromedial hypothalamic nucleus Weak
TS28: basomedial amygdaloid nucleus Weak Regionally restricted Expression is posterior.
TS28: mammillary body Weak Regionally restricted Expression is in the ventral and dorsal premammillary nucleus.
TS28: dentate gyrus Absent
TS28: hippocampus CA3 Absent
TS28: piriform cortex Absent
TS28: subiculum Absent


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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory