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Gene Expression Data
Assay Details
Assay
Reference: J:158452 Merte J, et al., Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol. 2010 Jan;12(1):41-6; sup pp 1-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698851
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Antibody: anti-Vangl2
Detection system: Secondary antibody
Results
Specimen 5 Wild-type: embryonic day 10.5 (more )
Note: Double labeled: red - Vangl2; green - Ctnnb1 (assay MGI:5698852).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Wild-type Vangl2 , 5_Wild-type Merge Expression is at the plasma membrane.
Specimen 5 Sec24bY613/Y613: embryonic day 10.5; Sec24bY613X/Sec24bY613X (more )
Note: Double labeled: red - Vangl2; green - Ctnnb1 (assay MGI:5698852).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Sec24bY613/613 Merge , 5_Sec24bY613/Y613 Vangl2 This mutant has decreased membrane localization and increased intracellular puncta.
Specimen 5 Vangl2LP/LP: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Note: Double labeled: red - Vangl2; green - Ctnnb1 (assay MGI:5698852).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Vangl2LP/LP Merge , 5_Vangl2LP/LP Vangl2 This mutant has decreased membrane localization and increased intracellular puncta.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory