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Gene Expression Data
Assay Details
Assay
Reference: J:158452 Merte J, et al., Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol. 2010 Jan;12(1):41-6; sup pp 1-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698852
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (2677)
Detection system: Secondary antibody
Results
Specimen 5 Wild-type: embryonic day 10.5 (more )
Note: Double labeled: green - Ctnnb1; red - Vangl2 (assay MGI:5698851).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Wild-type b-Catenin , 5_Wild-type Merge Expression is at the plasma membrane.

Specimen 5 Sec24bY613/Y613: embryonic day 10.5; Sec24bY613X/Sec24bY613X (more )
Note: Double labeled: green - Ctnnb1; red - Vangl2 (assay MGI:5698851).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Sec24bY613/613 Merge , 5_Sec24bY613/Y613 b-Catenin Expression in this mutant is the same as in wild-type embryos.

Specimen 5 Vangl2LP/LP: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Note: Double labeled: green - Ctnnb1; red - Vangl2 (assay MGI:5698851).
Structure Level Pattern Image Note
TS17: neural tube Present 5_Vangl2LP/LP Merge , 5_Vangl2LP/LP b-Catenin Expression in this mutant is the same as in wild-type embryos.

Specimen S5 WT: embryonic day 10.5 (more )
Note: Double labeled: green - Ctnnb1; red - Fzd3 (assay MGI:5698850).
Structure Level Pattern Image Note
TS17: neural tube Present S5_WT Merge , S5_WT B-Catenin Expression is at the plasma membrane.

Specimen S5 Y613: embryonic day 10.5; Sec24bY613X/Sec24bY613X (more )
Note: Double labeled: green - Ctnnb1; red - Fzd3 (assay MGI:5698850).
Structure Level Pattern Image Note
TS17: neural tube Present S5_Y613 Merge , S5_Y613 B-Catenin Expression in this mutant is the same as in wild-type embryos.

Specimen S5 Lp: embryonic day 10.5; Sec24bY613X/Sec24bY613X (more )
Note: Double labeled: green - Ctnnb1; red - Fzd3 (assay MGI:5698850).
Structure Level Pattern Image Note
TS17: neural tube Present S5_Lp B-Catenin , S5_Lp Merge Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory