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Gene Expression Data
Assay Details
Assay
Reference: J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698427
Gene symbol: Prkag1
Gene name: protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Results
Specimen 2J: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 2J Expression largely confined to neurons. Rare or no expression in astrocytes.
TS28: hippocampus pyramidal cell layer Present Regionally restricted 2J Expression in pyramidal cells.
TS28: spinal cord white matter Present Regionally restricted 2J Expression in some cells in white matter tracts with distribution of oligodendrocytes.
Specimen 3H: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Widespread 3H Expression largely confined to neurons. Widespread expression in all neurons.
Specimen 4H: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Widespread 4H Expression largely confined to neurons. Widespread neuronal expression.
TS28: main olfactory bulb glomerular layer Weak Regionally restricted 4H Light expression in glomeruli.
Specimen 5E: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: spinal cord Very strong Regionally restricted 5E Extremely high levels of expression in both nucleus and cytoplasm of motor neurons. Prominent axonal expression in both motor neurons and transversely cut white matter axons. Rare or no expression in astrocytes.
Specimen Table 1: postnatal (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted High expression in neurons. No expression in astrocytes.
TS28: hippocampus pyramidal cell layer Strong Regionally restricted High expression in pyramidal cells
TS28: hippocampus Present Regionally restricted No expression in astrocytes or activated astrocytes.
TS28: cerebellum Purkinje cell layer Strong Regionally restricted High expression in Purkinje cells. No expression in astrocytes.
TS28: cerebellum granule cell layer Present Regionally restricted Expression in granule cells. No expression in astrocytes.
TS28: spinal cord Present Regionally restricted Very high expression in motor neurons. No expression in astrocytes.
TS28: facial nucleus Strong Regionally restricted Very high expression in motor neurons.
TS28: main olfactory bulb granule cell layer Strong Regionally restricted High expression in mitral and granule cells.
TS28: main olfactory bulb mitral cell layer Strong Regionally restricted High expression in mitral and granule cells.
TS28: main olfactory bulb glomerular layer Present Regionally restricted 1A alpha1 Expression in periglomerular cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory