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Gene Expression Data
Assay Details
Assay
Reference: J:82501 Guazzi S, et al., HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain. Gene Expr Patterns. 2003 Mar;3(1):29-33
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5697283
Gene symbol: Hmgb1
Gene name: high mobility group box 1
Antibody: HMGB1 antibody
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1A: embryonic day 14.5 (more )
Note: Panels B and C are higher magnifications of the boxed areas in A.
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 1B , 1A Expression is in about 50% of the cells.
TS22: cortical plate Present 1B , 1A
TS22: thalamus Present 1A , 1C
TS22: cerebral cortex intermediate zone Absent 1B , 1A
TS22: cerebral cortex marginal layer Absent 1B , 1A
TS22: cortical subplate Absent 1B , 1A
Specimen 2A: embryonic day 16.0 (more )
Note: B is a higher magnification of the boxed area in A.
Structure Level Pattern Image Note
TS24: cortical plate Present 2A , 2B
TS24: cortical subplate Present 2A , 2B
TS24: cerebral cortex marginal layer Absent 2A , 2B
Specimen 2C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present Single cells 2C Expression is in scattered cells.
TS24: cerebral cortex subventricular zone Present Single cells 2C Expression is in scattered cells.
TS24: cerebral cortex ventricular layer Present Single cells 2C Expression is in scattered cells.
Specimen not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: telencephalon Weak Single cells Expression is in a few cells around the telencephalic vesicles.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory