Gene Expression Data
Assay Details
Assay
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Reference:
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J:160191
Xue XD, et al., A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10(LacZ) allele. Genesis. 2010 May;48(5):295-302
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5695475
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Gene symbol:
|
Tbx10
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Gene name:
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T-box 10
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Reporter:
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lacZ
|
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Direct Detection
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Results
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Specimen
not shown E9.5:
embryonic day 9.5; Tbx10tm1.1Miu/Tbx10 +
(more )
Specimen
not shown E9.5:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: rhombomere 4 |
Present |
Single cells |
|
Expression first detected in several individual cells in dorsal rhombomere 4.
|
Specimen
2a:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 9.75
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: rhombomere 4 |
Present |
Single cells |
2a
|
Expression in several individual cells in dorsal rhombomere 4.
|
Specimen
2b:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 9.75
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: rhombomere 4 |
Present |
Single cells |
2b
|
Expression in several individual cells in dorsal rhombomere 4.
|
Specimen
not shown E9.75:
embryonic day 9.75; Tbx10tm1.1Miu/Tbx10 +
(more )
Specimen
not shown E9.75:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 9.75
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: rhombomere 6 |
Present |
Single cells |
|
Expression in several cells in the dorsal-lateral margin of rhombomere 6 close to the otic vesicle.
|
Specimen
2c:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: embryo |
Present |
Regionally restricted |
2c
|
Authors report a restricted pattern of expression.
|
Specimen
2d:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: rhombomere 4 |
Present |
Regionally restricted |
2d
|
Expression in a increased number of cells compared to E9.75.
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TS17: rhombomere 6 |
Present |
Regionally restricted |
2d
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Expression in a increased number of cells compared to E9.75. Expressing cells dispersed across the ventral rhombomere without a prominent organization.
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Specimen
2e:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: rhombomere 4 |
Present |
Regionally restricted |
2e
|
Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.
|
TS17: rhombomere 6 |
Present |
Regionally restricted |
2e
|
Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.
|
Specimen
2g:
embryonic day 10.5; Tbx10tm1.1Miu/Tbx10 +
(more )
Note: Flat mount specimen.
Specimen
2g:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Note:
|
Flat mount specimen.
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: rhombomere 4 |
Present |
Regionally restricted |
2g
|
Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.
|
TS17: rhombomere 6 |
Present |
Regionally restricted |
2g
|
Expressing cells dispersed across the ventral rhombomere without a prominent organization.
|
Specimen
2h,h':
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
2h'
,
2h
|
Expression in cells distributed underneath the neuroepithelium.
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Specimen
2i,i':
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
2i
,
2i'
|
Expression in cells distributed underneath the neuroepithelium.
|
Specimen
2j:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
2j
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Expression in a mass of cells in ventral hindbrain on side of the floor plate, at the end of a stripe of expression beside the ventral midline.
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Specimen
2k:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
2k
|
Expression in two masses of cells in ventral hindbrain on each side of floor plate, at the ends of stripes of expression beside the ventral midline.
|
Specimen
2k':
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
2k'
|
Expression in an accumulation of cells in rhombomere 4. Expression in cell stripes.
|
Specimen
2l:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
2l
|
Expression in cell masses in rhombomere 4. Authors report expression in cell stripes have almost disappeared; only a few individual cells could be detected. Expression in rhombomere 6 no longer visible.
|
Specimen
2m:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
2m
|
Expression in cell masses in rhombomere 4. Authors report expression in cell stripes have almost disappeared; only a few individual cells could be detected. Expression in rhombomere 6 no longer visible.
|
Specimen
3a:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
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Type:
|
section
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pons |
Present |
Regionally restricted |
3a
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Expression in the caudal pons. Rostral parts of bands of expression located in subcoeruleus nucleus (SnC), lateral to caudal pontine reticular nucleus (PnC) and medial to trigeminal motor nucleus (Mo5).
|
Specimen
3b:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pons |
Present |
Regionally restricted |
3b
|
Expression in the caudal pons. Rostral parts of bands of expression located in subcoeruleus nucleus (SnC), lateral to caudal pontine reticular nucleus (PnC) and medial to trigeminal motor nucleus (Mo5).
|
Specimen
3c:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pons |
Present |
Regionally restricted |
3c
|
Expression in 2 longitudinal bands extending dorsal to caudal half of superior olivary nucleus and rostral end of facial nucleus. Rostral parts in subcoeruleus nucleus, lateral to caudal pontine reticular nucleus and medial to trigeminal motor nucleus.
|
Specimen
3d:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pons |
Present |
Regionally restricted |
3d
|
Expression in 2 longitudinal bands extending dorsal to caudal half of superior olivary nucleus and rostral end of facial nucleus. Caudal parts of bands in intermediate reticular formation, lateral to pontine reticular nucleus and medial to facial nerve.
|
Specimen
3e:
postnatal day 0; Tbx10tm1.1Miu/Tbx10 +
(more )
Note: Double labeled: blue - Tbx10; brown - Th (assay MGI:5695477).
Specimen
3e:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Note:
|
Double labeled: blue - Tbx10; brown - Th (assay MGI:5695477).
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: pons |
Present |
Regionally restricted |
3e
|
Expression ventral to the locus coeruleus.
|
Specimen
4a:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: pons |
Present |
Regionally restricted |
4a
|
Expression in the caudal pons similar to that seen in P0 mice.
|
Specimen
4b:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: pons |
Present |
Regionally restricted |
4b
|
Expression in the caudal pons similar to that seen in P0 mice.
|
Specimen
4c:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: pons |
Present |
Regionally restricted |
4c
|
Expression in the caudal pons similar to that seen in P0 mice.
|
Specimen
4d:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: pons |
Present |
Regionally restricted |
4d
|
Expression in the caudal pons similar to that seen in P0 mice.
|
Specimen
5b:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
5b
|
Expression in cells located lateral to facial motor neurons.
|
Specimen
5b':
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Mutant Allele(s):
|
Tbx10tm1.1Miu/Tbx10+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Other - See Notes
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: hindbrain |
Present |
Regionally restricted |
5b'
|
Expression in ventral interneurons in ventrolateral area.
|
|