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Gene Expression Data
Assay Details
Assay
Reference: J:160191 Xue XD, et al., A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10(LacZ) allele. Genesis. 2010 May;48(5):295-302
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5695475
Gene symbol: Tbx10
Gene name: T-box 10
Reporter: lacZ
Direct Detection
Results
Specimen not shown E9.5: embryonic day 9.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS15: rhombomere 4 Present Single cells Expression first detected in several individual cells in dorsal rhombomere 4.

Specimen 2a: embryonic day 9.75; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS16: rhombomere 4 Present Single cells 2a Expression in several individual cells in dorsal rhombomere 4.

Specimen 2b: embryonic day 9.75; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS16: rhombomere 4 Present Single cells 2b Expression in several individual cells in dorsal rhombomere 4.

Specimen not shown E9.75: embryonic day 9.75; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS16: rhombomere 6 Present Single cells Expression in several cells in the dorsal-lateral margin of rhombomere 6 close to the otic vesicle.

Specimen 2c: embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2c Authors report a restricted pattern of expression.

Specimen 2d: embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present Regionally restricted 2d Expression in a increased number of cells compared to E9.75.
TS17: rhombomere 6 Present Regionally restricted 2d Expression in a increased number of cells compared to E9.75. Expressing cells dispersed across the ventral rhombomere without a prominent organization.

Specimen 2e: embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present Regionally restricted 2e Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.
TS17: rhombomere 6 Present Regionally restricted 2e Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.

Specimen 2g: embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Note: Flat mount specimen.
Structure Level Pattern Image Note
TS17: rhombomere 4 Present Regionally restricted 2g Roughly organized cell stripes of expression, crossing ventral rhombomere 4 towards the floor plate.
TS17: rhombomere 6 Present Regionally restricted 2g Expressing cells dispersed across the ventral rhombomere without a prominent organization.

Specimen 2h,h': embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2h' , 2h Expression in cells distributed underneath the neuroepithelium.

Specimen 2i,i': embryonic day 10.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2i , 2i' Expression in cells distributed underneath the neuroepithelium.

Specimen 2j: embryonic day 11.0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2j Expression in a mass of cells in ventral hindbrain on side of the floor plate, at the end of a stripe of expression beside the ventral midline.

Specimen 2k: embryonic day 11.0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2k Expression in two masses of cells in ventral hindbrain on each side of floor plate, at the ends of stripes of expression beside the ventral midline.

Specimen 2k': embryonic day 11.0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2k' Expression in an accumulation of cells in rhombomere 4. Expression in cell stripes.

Specimen 2l: embryonic day 11.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2l Expression in cell masses in rhombomere 4. Authors report expression in cell stripes have almost disappeared; only a few individual cells could be detected. Expression in rhombomere 6 no longer visible.

Specimen 2m: embryonic day 11.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2m Expression in cell masses in rhombomere 4. Authors report expression in cell stripes have almost disappeared; only a few individual cells could be detected. Expression in rhombomere 6 no longer visible.

Specimen 3a: postnatal day 0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS27: pons Present Regionally restricted 3a Expression in the caudal pons. Rostral parts of bands of expression located in subcoeruleus nucleus (SnC), lateral to caudal pontine reticular nucleus (PnC) and medial to trigeminal motor nucleus (Mo5).

Specimen 3b: postnatal day 0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS27: pons Present Regionally restricted 3b Expression in the caudal pons. Rostral parts of bands of expression located in subcoeruleus nucleus (SnC), lateral to caudal pontine reticular nucleus (PnC) and medial to trigeminal motor nucleus (Mo5).

Specimen 3c: postnatal day 0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS27: pons Present Regionally restricted 3c Expression in 2 longitudinal bands extending dorsal to caudal half of superior olivary nucleus and rostral end of facial nucleus. Rostral parts in subcoeruleus nucleus, lateral to caudal pontine reticular nucleus and medial to trigeminal motor nucleus.

Specimen 3d: postnatal day 0; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS27: pons Present Regionally restricted 3d Expression in 2 longitudinal bands extending dorsal to caudal half of superior olivary nucleus and rostral end of facial nucleus. Caudal parts of bands in intermediate reticular formation, lateral to pontine reticular nucleus and medial to facial nerve.

Specimen 3e: postnatal day 0; Tbx10tm1.1Miu/Tbx10+ (more )
Note: Double labeled: blue - Tbx10; brown - Th (assay MGI:5695477).
Structure Level Pattern Image Note
TS27: pons Present Regionally restricted 3e Expression ventral to the locus coeruleus.

Specimen 4a: postnatal adult; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS28: pons Present Regionally restricted 4a Expression in the caudal pons similar to that seen in P0 mice.

Specimen 4b: postnatal adult; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS28: pons Present Regionally restricted 4b Expression in the caudal pons similar to that seen in P0 mice.

Specimen 4c: postnatal adult; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS28: pons Present Regionally restricted 4c Expression in the caudal pons similar to that seen in P0 mice.

Specimen 4d: postnatal adult; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS28: pons Present Regionally restricted 4d Expression in the caudal pons similar to that seen in P0 mice.

Specimen 5b: embryonic day 11.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 5b Expression in cells located lateral to facial motor neurons.

Specimen 5b': embryonic day 11.5; Tbx10tm1.1Miu/Tbx10+ (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 5b' Expression in ventral interneurons in ventrolateral area.


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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory