Tbx10^tm1.1Miu
Targeted Allele Detail

Summary

• Symbol: Tbx10^tm1.1Miu
• Name: T-box 10; targeted mutation 1.1, Naoyuki Miura
• MGI ID: MGI:4459542
• Gene: Tbx10 Location: Chr19:4042752-4049512 bp, + strand Genetic Position: Chr19, 3.71 cM, cytoband A
• Alliance: Tbx10^tm1.1Miu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160191
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: The 3' half of exon 2 up to the 5' half of exon 8 was replaced with an in-frame nls-LacZ gene by homologous recombination. In addition, a FRT-flanked Neo cassette was inserted 3'. The selection casette has been removed by flp mediated recombination. (J:160191)

Generation of the Tbx10^tm1.1Miu allele

Expression

In Mice Carrying this Mutation:

34 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx10 Mutation: 16 strains or lines available

References

• Original: J:160191 Xue XD, et al., A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10(LacZ) allele. Genesis. 2010 May;48(5):295-302
• All: 1 reference(s)