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Gene Expression Data
Assay Details
Assay
Reference: J:84432 Qi Y, et al., Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50
Assay type: RNA in situ
MGI Accession ID: MGI:5694635
Gene symbol: Mbp
Gene name: myelin basic protein
Probe: Mbp probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Present Regionally restricted 5A Expression was detected in a small number of oligodendrocytes in the ventral spinal cord.

Specimen 5B: embryonic day 16.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS24: spinal cord Absent 5B

Specimen 5C: embryonic day 18.5 (more )
Note: Section from the thoracic region.
Structure Level Pattern Image Note
TS26: spinal cord Present Regionally restricted 5C Expression was detected in oligodendrocytes.

Specimen 5D: embryonic day 18.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: Section from the thoracic region.
Structure Level Pattern Image Note
TS26: spinal cord Present Regionally restricted 5D Expression was detected in a few oligodendrocytes, but much fewer than in wild type.

Specimen 5E: embryonic day 18.5 (more )
Note: Section from the cervical region.
Structure Level Pattern Image Note
TS26: spinal cord Present Regionally restricted 5E Expression was detected in oligodendrocytes.

Specimen 5F: embryonic day 18.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: Section from the cervical region.
Structure Level Pattern Image Note
TS26: spinal cord Present Regionally restricted 5F In the cervical spinal cord of the mutants, expression was detected in many more oligodendrocytes than at the thoracic level of the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory