Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Krt19-cre/ERT2)#Tcw
Name:	transgene insertion, Timothy C Wang
MGI ID:	MGI:5692448
Synonyms:	Krt19-CreERT2
Transgene:	Tg(Krt19-cre/ERT2)#Tcw  Location: unknown
Alliance:	Tg(Krt19-cre/ERT2)#Tcw page

Strain of Origin:

CBA x C57BL/6J

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Krt19-cre/ERT2)#Tcw expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Krt19 (MGI:96693)   Mutation details: BAC RP-23-24N13 was used to generate containing an inducible cre recombinase gene (cre/ERT2) inserted at the translation initiation site to achieve expression in the colon and intestine. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:224765)

Activity:	Tissue activity of this recombinase allele
Driver:	Krt19 (mouse) Summary of all recombinase alleles driven by Krt19. Comparative matrix view of recombinase activities Alliance mouse Krt19 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:224765 Asfaha S, et al., Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. Cell Stem Cell. 2015 Jun 4;16(6):627-38
All:	1 reference(s)