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Gene Expression Data
Assay Details
Assay
Reference: J:163834 Paudyal A, et al., The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
Assay type: RNA in situ
MGI Accession ID: MGI:5688976
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 8A-C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Present 8A
TS16: neural tube Present 8A
TS16: cranial ganglion Present 8B , 8A
TS16: dorsal root ganglion Present 8A , 8C
Specimen 8D-F: embryonic day 10.5; Ptk7chz/Ptk7+ (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Present 8D
TS16: neural tube Present 8D
TS16: cranial ganglion Present 8E , 8D
TS16: dorsal root ganglion Present 8D , 8F
Specimen 8G-I: embryonic day 10.5; Ptk7chz/Ptk7chz (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Present 8G Expression was detected in migrating neural crest, but the distribution appeared abnormal.
TS16: neural tube Present 8G The spinal region expression domain was narrower in the mutant.
TS16: cranial ganglion Present 8H , 8G
TS16: dorsal root ganglion Present 8I , 8G The normal V-shaped arrangement of cells was disturbed in the mutant.
Specimen 8J-L: embryonic day 10.5; Ptk7chz/Ptk7chz (more )
Structure Level Pattern Image Note
TS16: migrating neural crest Present 8J Expression was detected in migrating neural crest, but the distribution appeared abnormal.
TS16: neural tube Present 8J The spinal region expression domain was narrower in the mutant.
TS16: cranial ganglion Present 8J , 8K
TS16: dorsal root ganglion Present 8J , 8L The normal V-shaped arrangement of cells was disturbed in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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