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Gene Expression Data
Assay Details
Assay
Reference: J:109037 Kim HJ, et al., WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. J Neurosci. 2006 May 24;26(21):5849-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661379
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Antibody: Anti-Olig2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 6B WT: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present Regionally restricted 6B WT lower , 6B WT upper Expression was detected in oligodendrocytes in the corpus callosum.
TS28: corpus striatum Present 6B WT upper Expression was detected in oligodendrocytes.
TS28: frontal cortex Present 6B WT upper Expression was detected in oligodendrocytes.
TS28: telencephalon septum Present 6B WT upper Expression was detected in oligodendrocytes.
Specimen 6B Wave1-/-: postnatal day 20; Wasf1Gt(VICTR37)1Kwak/Wasf1Gt(VICTR37)1Kwak (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present Regionally restricted 6B Wave1-/- upper , 6B Wave1-/- lower In the corpus callosum there was a fourfold reduction in the total number of immunopositive cells in the mutant compared to wild type. However, the cell density per unit area was the same as in the wild type.
TS28: corpus striatum Present Regionally restricted 6B Wave1-/- upper A higher density of immunopositive cells was noted in other regions of the mutant brain compared to wild type.
TS28: frontal cortex Present Regionally restricted 6B Wave1-/- upper A higher density of immunopositive cells was noted in other regions of the mutant brain compared to wild type.
TS28: telencephalon septum Present Regionally restricted 6B Wave1-/- upper A higher density of immunopositive cells was noted in other regions of the mutant brain compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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