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Gene Expression Data
Assay Details
Assay
Reference: J:182578 Kay JN, et al., MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5660930
Gene symbol: Megf10
Gene name: multiple EGF-like-domains 10
Reporter: lacZ
Antibody: anti-B-galactosidase (Sanes)
Results
Specimen S6a: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10+ (more )
Note: Right image is double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6a right , S6a left Expression was detected in starburst amacrine cells, horizontal cells, and Muller glia.
TS28: retina ganglion cell layer Present Regionally restricted S6a right , S6a left Expression was detected in starburst amacrine cells.
TS28: retina inner plexiform layer Present Regionally restricted S6a left , S6a right Expression was detected in starburst amacrine cell dendrites, which project to two sublaminae in the inner plexiform layer.

Specimen S6c: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10+ (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6c Expression was detected in Muller glia.
TS28: retina outer nuclear layer Present Regionally restricted S6c Radial processes of Muller glia were noted in the outer nuclear layer.

Specimen S6d: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs (more )
Note: Right image is double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6d left , S6d right Expression was detected in starburst amacrine cells, horizontal cells and Muller glia.
TS28: retina ganglion cell layer Present Regionally restricted S6d left , S6d right Expression was detected in starburst amacrine cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory