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Gene Expression Data
Assay Details
Assay
Reference: J:182578 Kay JN, et al., MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660817
Gene symbol: Megf10
Gene name: multiple EGF-like-domains 10
Antibody: Anti-Megf10
Results
Specimen 1f: postnatal day 3 (more )
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present Regionally restricted 1f top , 1f bottom Expression was detected in the somata and processes of developing starburst amacrine cells.
TS27: retina inner nuclear layer Present Regionally restricted 1f top , 1f bottom Expression was detected in the somata and processes of developing starburst amacrine cells.
TS27: retina inner plexiform layer Present Regionally restricted 1f top , 1f bottom Expression was detected in the somata and processes of developing starburst amacrine cells.
Specimen S1c: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: retina inner nuclear layer Present Regionally restricted S1c center , S1c left , S1c right Expression was detected in starburst amacrine cells and horizontal cells.
TS27: retina ganglion cell layer Present Regionally restricted S1c center , S1c left Expression was detected in starburst amacrine cells.
TS27: retina inner plexiform layer Present Regionally restricted S1c center , S1c left Expression was detected in starburst amacrine cell processes.
TS27: retina outer plexiform layer Present Regionally restricted S1c left , S1c right Expression was detected in horizontal cell processes.
Specimen S1d +/+: postnatal day 3 (more )
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present Regionally restricted S1d +/+ right , S1d +/+ center Expression was detected in starburst amacrine cells.
TS27: retina inner nuclear layer Present Regionally restricted S1d +/+ right , S1d +/+ center Expression was detected in starburst amacrine cells.
Specimen S1d -/-: postnatal day 3; Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs (more )
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Absent S1d -/- center , S1d -/- right
TS27: retina inner nuclear layer Absent S1d -/- center , S1d -/- right
Specimen S7a P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: retina inner nuclear layer Present Regionally restricted S7a P0 Expression was detected in horizontal cells and the vertically-oriented dendrites.
Specimen S7a P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S7a P7 Expression was detected in horizontal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory