Megf10 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:182578 Kay JN, et al., MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5660817
Gene symbol:	Megf10
Gene name:	multiple EGF-like-domains 10

Antibody:

Anti-Megf10

Results

Specimen 1f: postnatal day 3 (more

)
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).

Structure	Level	Pattern	Image	Note
TS27: retina ganglion cell layer	Present	Regionally restricted	1f top , 1f bottom	Expression was detected in the somata and processes of developing starburst amacrine cells.
TS27: retina inner nuclear layer	Present	Regionally restricted	1f top , 1f bottom	Expression was detected in the somata and processes of developing starburst amacrine cells.
TS27: retina inner plexiform layer	Present	Regionally restricted	1f top , 1f bottom	Expression was detected in the somata and processes of developing starburst amacrine cells.

Specimen S1c: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: retina inner nuclear layer	Present	Regionally restricted	S1c center , S1c left , S1c right	Expression was detected in starburst amacrine cells and horizontal cells.
TS27: retina ganglion cell layer	Present	Regionally restricted	S1c center , S1c left	Expression was detected in starburst amacrine cells.
TS27: retina inner plexiform layer	Present	Regionally restricted	S1c center , S1c left	Expression was detected in starburst amacrine cell processes.
TS27: retina outer plexiform layer	Present	Regionally restricted	S1c left , S1c right	Expression was detected in horizontal cell processes.

Specimen S1d +/+: postnatal day 3 (more

)
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).

Structure	Level	Pattern	Image	Note
TS27: retina ganglion cell layer	Present	Regionally restricted	S1d +/+ right , S1d +/+ center	Expression was detected in starburst amacrine cells.
TS27: retina inner nuclear layer	Present	Regionally restricted	S1d +/+ right , S1d +/+ center	Expression was detected in starburst amacrine cells.

Specimen S1d -/-: postnatal day 3; Megf10^{tm1a(KOMP)Jrs}/Megf10^{tm1a(KOMP)Jrs} (more

)
Note: Double labeled: green - Megf10; red - Chat (assay MGI:5660818).

Structure	Level	Pattern	Image	Note
TS27: retina ganglion cell layer	Absent		S1d -/- center , S1d -/- right
TS27: retina inner nuclear layer	Absent		S1d -/- center , S1d -/- right

Specimen S7a P0: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: retina inner nuclear layer	Present	Regionally restricted	S7a P0	Expression was detected in horizontal cells and the vertically-oriented dendrites.

Specimen S7a P7: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: retina inner nuclear layer	Present	Regionally restricted	S7a P7	Expression was detected in horizontal cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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