b2b3077.2Clo
Chemically induced Allele Detail
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| Symbol: |
b2b3077.2Clo |
| Name: |
Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo |
| MGI ID: |
MGI:5646614 |
| Synonyms: |
Po |
| Gene: |
b2b3077.2Clo Location: unknown
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| Alliance: |
b2b3077.2Clo page
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Mutant 3077-006-4 (E15.5) exhibits aortic atresia with accessory anterior lung lobes, hypoplastic left atrium, and thickened left ventricle wall. This is diagnosed as aortic atresia, left venricle hypertrophy, and hypoplastic left heart syndrome (HLHS) spectrum heart by ECM histopathology.
Show the 10 phenotype image(s) involving this allele.
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| Strain of Origin: |
C57BL/6J
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| Project Collection: |
B2B/CvDC
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| Allele Type: |
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Chemically induced (ENU) |
| Mutation: |
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Undefined
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Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b3077Clo.
(J:175213)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any b2b3077.2Clo Mutation: |
0 strains or lines available
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Summative Diagnosis:
Cardiovascular phenotypes: Hypoplastic left ventricle (LV), aortic atresia, and hypoplastic mitral, phenotypes consistent with hypoplastic left heart syndrome (HLHS).
Noncardiovascular phenotype: Severe craniofacial defect with short snout, micrognathia, cleft lip and palate, hypoplastic thymus, hypoplastic and accessory anterior lung lobes, renal anomalies, short gut, club limbs, bobtail, and syndatcyly.
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Analysis Tools
