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Itm2atm1.1Iho
Targeted Allele Detail
Summary
Symbol: Itm2atm1.1Iho
Name: integral membrane protein 2A; targeted mutation 1.1, I-Cheng Ho
MGI ID: MGI:5645968
Gene: Itm2a  Location: ChrX:106440801-106446966 bp, - strand  Genetic Position: ChrX, 47.52 cM, cytoband A2-A3
Alliance: Itm2atm1.1Iho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217351
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 2-6 flanked by two loxP sites and a Frt-flanked neo cassette before the second loxP site were inserted via homologous recombination. Cre-mediated recombination removed exons 2-6 and the neo-cassette. (J:217351)
Generation of the Itm2atm1Iho and Itm2atm1.1Iho alleles
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itm2a Mutation:  5 strains or lines available
References
Original:  J:217351 Tai TS, et al., Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells. PLoS One. 2014;9(5):e96535
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory