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Gene Expression Data
Assay Details
Assay
Reference: J:17839 Wu JE, et al., Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn. 1994 Apr;199(4):292-314
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5643935
Gene symbol: Itga2
Gene name: integrin alpha 2
Antibody: MA2 antibody
Results
Specimen 7E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present Regionally restricted 7E Expression is in the small vessel endothelium in the skin.
TS26: epidermis basal layer Present 7E

Specimen 7F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: skin Present Graded 7F There is increasing intensity towards the base of the facial skin.
TS26: blood vessel endothelium Present 7F
TS26: hair follicle Present 7F

Specimen 7H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: liver Present Single cells 7H Expression is in megakaryocytes.

Specimen 8C/C': postnatal adult (more )
Note: Gestational age E8.5.
Structure Level Pattern Image Note
TS28: decidua Present 8C/C' Expression is in cells proximal to the implanted embryo.

Specimen 8F: postnatal adult (more )
Note: Gestational age E11.5.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 8F Expression is in decidual cells surrounding the vessels.
TS28: blood vessel endothelium Present 8F

Specimen 8I: postnatal adult (more )
Note: Gestational age E8.5
Structure Level Pattern Image Note
TS28: decidua basalis Present Regionally restricted 8I Expression is in the basal zone adjacent to the myometrium.

Specimen 8J embryo: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trophoblast giant cell Absent 8J

Specimen 8J mother: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 8J Expression is in mesenchymal cells especially at the tip of the mucosal fold.
TS28: decidua capsularis Strong 8J

Specimen 9C embryo: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: spongiotrophoblast Present 9C
TS19: labyrinthine zone Absent 9C
TS19: trophoblast giant cell Absent 9C

Specimen 9C mother: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present 9C

Specimen 10G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cartilage Present 10G Expression is in hypertrophic chondrocytes and in cells at the wave front of endochondrial ossification.

Specimen 10H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bone Present 10H

Specimen 11C: embryonic day 18.5 (more )
Note: Bell stage of molar tooth development.
Structure Level Pattern Image Note
TS26: stellate reticulum Strong 11C
TS26: molar dental lamina Absent 11C

Specimen 11F,G: embryonic day 18.5 (more )
Note: (G) is a higher magnification of the boxed area in (F).
Structure Level Pattern Image Note
TS26: incisor enamel organ Present 11F Expression is strong in the stellate reticulum and moderate in the ameloblasts.
TS26: incisor Strong 11F , 11G Expression is in odontoblasts. Expression was particularily strong on the cell processes extruding the collagenous matrix of the dentin.
TS26: stellate reticulum Strong 11G , 11F

Specimen 12C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine mesenchyme Moderate Regionally restricted 12C Expression is in cells proximal to the epithelium.
TS24: intestine epithelium Weak 12C
TS24: intestine smooth muscle Absent 12C

Specimen 12F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine mesenchyme Strong Regionally restricted 12F Expression is at the tips of the villi.
TS24: intestine epithelium Trace 12F

Specimen 12I: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: intestine wall Present Regionally restricted 12I Expression is on the mesenchymal tissues of the lamina propria especially at the villus tips.
TS27: intestine epithelium Present 12I

Specimen 12L: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 12L Expression is in the epithelial cells of the intestinal crypts.
TS28: blood vessel endothelium Present 12L
TS28: small intestine lamina propria Absent 12L

Specimen 13G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Present Regionally restricted 13G Expression is in mesenchymal cells that align in a tubular fashion, absent in cells adjacent to the epithelium.
TS21: lung epithelium Absent 13G

Specimen 13I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung mesenchyme Present Widespread 13I Widespread expression, absent in smooth muscle adjacent to bronchioles.
TS24: bronchiole epithelium Absent 13I

Specimen 14A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart ventricle Present Regionally restricted 14A Expression is in a group of cells traversing the ventricle.

Specimen 14B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: aortico-pulmonary spiral septum Strong 14B
TS20: heart Strong Regionally restricted 14B Expression is in the valve swellings.

Specimen 14C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart valve Present Single cells 14C Expression is in the bulbo-truncal junction and in cells lining the valve swellings.

Specimen 14D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal aorta Present Single cells 14D
TS21: pulmonary trunk Present Single cells 14D

Specimen not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: aorta Weak Regionally restricted Expression is in the muscular layer.
TS26: pulmonary trunk Weak Regionally restricted Expression is in the muscular layer.

Specimen not shown A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: aorta smooth muscle Absent
TS28: lens Absent
TS28: pulmonary trunk Absent

Specimen 15C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Weak 15C
TS20: retina Absent 15C

Specimen 15F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens Strong 15F
TS26: cornea epithelium Present 15F
TS26: retina Absent 15F

Specimen 16C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: adrenal cortex Present 16C
TS27: adrenal medulla Absent 16C

Specimen 16D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adrenal cortex Present Regionally restricted 16D Expression is reduced at the periphery of the cortex.
TS28: adrenal medulla Absent 16D

Specimen 16E: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: adrenal gland Absent 16E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory