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Gene Expression Data
Assay Details
Assay
Reference: J:17839 Wu JE, et al., Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn. 1994 Apr;199(4):292-314
Assay type: RNA in situ
MGI Accession ID: MGI:5643932
Gene symbol: Itga2
Gene name: integrin alpha 2
Probe: pBSMA21
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 7C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 7C Expression is in the basal layer.
TS24: blood vessel endothelium Present Regionally restricted 7C Expression is in the small vessel endothelium in the skin.

Specimen 7G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Present Single cells 7G Expression is in megakaryocytes.

Specimen 8A/B: postnatal adult (more )
Note: Gestational age E7.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 8A/B Expression is around the implantation site.

Specimen 8D/E: postnatal adult (more )
Note: Gestational age E10.5.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 8D/E Expression is in decidual cells surrounding the vessels.

Specimen 8G/H: postnatal adult (more )
Note: Gestational age E10.5.
Structure Level Pattern Image Note
TS28: decidua basalis Present 8G/H Expression is in stromal cells at the basal zone.
TS28: myometrium Absent 8G/H

Specimen 9A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present 9A/B
TS20: labyrinthine zone Absent 9A/B
TS20: trophoblast giant cell Absent 9A/B

Specimen 9A/B mother: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present 9A/B

Specimen 10A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cartilage Present 10A/B Expression is in hypertrophic chondrocytes.

Specimen 10C/D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cartilage Present Regionally restricted 10C/D Expression is in hypertrophic chondrocytes.
TS23: skeleton Present Regionally restricted 10C/D Expression is in osteoclasts and in osteocytes not embedded in the bone matrix. Absent in osteocytes already embedded in bone matrix.

Specimen 11A/B: embryonic day 16.5 (more )
Note: Bell stage of incisor tooth development.
Structure Level Pattern Image Note
TS24: stellate reticulum Strong 11A/B
TS24: dental lamina Absent 11A/B

Specimen 11D/E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: stellate reticulum Present 11D/E
TS26: inner enamel epithelium Moderate Regionally restricted 11D/E Expression is moderate in the ameloblasts.
TS26: incisor Strong Regionally restricted 11D/E Expression is in odontoblasts.

Specimen 12A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine mesenchyme Moderate Regionally restricted 12A/B Expression is in cells proximal to the epithelium.
TS24: intestine epithelium Weak 12A/B
TS24: intestine smooth muscle Absent 12A/B

Specimen 12D/E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: embryo Strong 12D/E Expression is in subepithelial mesenchymal tissue and is strong at the tips of the villi.
TS24: intestine epithelium Trace 12D/E

Specimen 12G/H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: intestine wall Strong Regionally restricted 12G/H Expression is in the mesenchyme at the tips of the villi.
TS27: intestine epithelium Moderate 12G/H

Specimen 13A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung mesenchyme Present 13A/B

Specimen 13E/F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 13E/F Expression is in some of the loose mesenchymal cells, absent in smooth muscle.
TS20: lung epithelium Absent 13E/F

Specimen 14E/F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: aorta Strong Regionally restricted 14E/F Expression is in the walls.
TS24: heart Strong Regionally restricted 14E/F Expression is at the junction between the heart and the pulmonary trunk.
TS24: pulmonary trunk Strong Regionally restricted 14E/F Expression is at the junction between the heart and the pulmonary trunk.

Specimen not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: aorta Weak Regionally restricted Expression is in the muscular layer.
TS26: pulmonary trunk Weak Regionally restricted Expression is in the muscular layer.

Specimen not shown A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: aorta smooth muscle Absent
TS28: lens Absent
TS28: pulmonary trunk Absent

Specimen 15A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens Weak 15A/B
TS21: retina Absent 15A/B

Specimen 15D/E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens Present 15D/E
TS23: retina Absent 15D/E

Specimen 16A/B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: adrenal cortex Present Regionally restricted 16A/B Absent at the periphery of the cortex.
TS27: adrenal medulla Absent 16A/B


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory