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Gene Expression Data
Assay Details
Assay
Reference: J:198000 Hoffmann S, et al., Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia. Basic Res Cardiol. 2013;108(2):339
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641478
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Antibody: anti-HCN4 (APC-052)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 2Ba,c: embryonic day 11.5 (more )
Note: Double labeled: green - Hcn4; red - Isl1 (assay MGI:5641477).
Structure Level Pattern Image Note
TS19: sinoatrial node Present 2Ba , 2Bc
Specimen 2Bd,f: embryonic day 11.5; Shox2tm1Acgg/Shox2tm1Acgg (more )
Note: Double labeled: green - Hcn4; red - Isl1 (assay MGI:5641477).
Structure Level Pattern Image Note
TS19: sinoatrial node Present 2Bd , 2Bf Expression was detected as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory