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Gene Expression Data
Assay Details
Assay
Reference: J:198000 Hoffmann S, et al., Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia. Basic Res Cardiol. 2013;108(2):339
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641477
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 2Ba,b: embryonic day 11.5 (more )
Note: Double labeled: red - Isl1; green - Hcn4 (assay MGI:5641478).
Structure Level Pattern Image Note
TS19: sinoatrial node Present 2Ba , 2Bb
Specimen 2Bd,e: embryonic day 11.5; Shox2tm1Acgg/Shox2tm1Acgg (more )
Note: Double labeled: red - Isl1; green - Hcn4 (assay MGI:5641478).
Structure Level Pattern Image Note
TS19: sinoatrial node Absent 2Be , 2Bd
Specimen 2Bg,h: embryonic day 11.5 (more )
Note: Double labeled: red - Isl1; green - Tbx18 (assay MGI:5641479).
Structure Level Pattern Image Note
TS19: sinoatrial node Present 2Bh , 2Bg
Specimen 2Bj,k: embryonic day 11.5; Shox2tm1Acgg/Shox2tm1Acgg (more )
Note: Double labeled: red - Isl1; green - Tbx18 (assay MGI:5641479).
Structure Level Pattern Image Note
TS19: sinoatrial node Absent 2Bj , 2Bk
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory