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Gene Expression Data
Assay Details
Assay
Reference: J:175242 Togashi H, et al., Nectins establish a checkerboard-like cellular pattern in the auditory epithelium. Science. 2011 Aug 26;333(6046):1144-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641217
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1 mAb
Results
Specimen 2A WT: postnatal day 1 (more )
Note: Double labeled: red - Tjp1; green - F-actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present 2A ZO-1

Specimen 2B Nectin-1 KO: postnatal day 1; Nectin1tm1Ytk/Nectin1tm1Ytk (more )
Note: Double labeled: red - Tjp1; green - F-actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2B ZO-1 Authors report expression at aberrantly formed contact cells between hair cells, and abnormally formed junctions between phalangeal cells.

Specimen 2C Nectin-2 KO: postnatal day 1; Nectin2tm1Smu/Nectin2tm1Smu (more )
Note: Double labeled: red - Tjp1; green - F-actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present 2C ZO-1

Specimen 2D Nectin-3 KO: postnatal day 1; Nectin3tm1Ytk/Nectin3tm1Ytk (more )
Note: Double labeled: red - Tjp1; green - F-actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present 2D ZO-1 Authors report expression at aberrantly formed contact cells between hair cells, and abnormally formed junctions between phalangeal cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory