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Gene Expression Data
Assay Details
Assay
Reference: J:175242 Togashi H, et al., Nectins establish a checkerboard-like cellular pattern in the auditory epithelium. Science. 2011 Aug 26;333(6046):1144-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641215
Gene symbol: Nectin2
Gene name: nectin cell adhesion molecule 2
Antibody: anti-nectin-2
Results
Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted 3C Nectin-2 Expression at junctions between auditory epithelia.

Specimen 1 Nectin-2: postnatal day 1 (more )
Note: Double labeled: green - Nectin2; red - Myo7a (assay MGI:5641213)
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 1_Nectin-2/MyoVIIa , 1_Nectin-2 Uniform expression at boundaries between hair cells and supporting cells, as well as between supporting cells.

Specimen 3A WT: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: organ of Corti Present 3A Nectin-2

Specimen 3B Nectin-1 KO: postnatal day 1; Nectin1tm1Ytk/Nectin1tm1Ytk (more )
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3B Nectin-2 Authors report expression was not altered compared to wild type mice.

Specimen 3C Nectin-2 KO: postnatal day 1; Nectin2tm1Smu/Nectin2tm1Smu (more )
Structure Level Pattern Image Note
TS27: organ of Corti Absent 3C Nectin-2

Specimen 3D Nectin-3 KO: postnatal day 1; Nectin3tm1Ytk/Nectin3tm1Ytk (more )
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3D Nectin-2 Authors report expression was not altered compared to wild type mice.

Specimen S2B Nectin-2: embryonic day 16.0 (more )
Note: Double labeled: green - Nectin2; red - Myo7a (assay MGI:5641213)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted S2B Nectin-2/MyoVIIa , S2B Nectin-2 Expression at apical surface of auditory epithelium in middle turn of cochlea. Authors report expression at E16 similar to that at P1.

Specimen S3B Nectin-2: embryonic day 16.0 (more )
Note: Double labeled: green - Nectin2; red - Myo7a (assay MGI:5641213)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted S3B Nectin-2 , S3B Nectin-2/MyoVIIa Expression localized on apical side of lateral membranes of hair cells and supporting cells.

Specimen S3E Nectin-2: embryonic day 16.0 (more )
Note: Double labeled: green - Nectin2; red - Myo7a (assay MGI:5641213)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted S3E Nectin-2/MyoVIIa , S3E Nectin-2 Expression localized on apical side of lateral membranes of hair cells and supporting cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory