Gene Expression Data
Assay Details
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Assay
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Reference:
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J:193641
Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5639311
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Gene symbol:
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Myo7a
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Gene name:
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myosin VIIA
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Results
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Specimen
3F bv/+:
postnatal day 5; Srrm4bv/Srrm4 +
(more  )
Specimen
3F bv/+:
(close  )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Srrm4bv/Srrm4+
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
3F bv/+
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Expression was detected in the inner hair cells and the outer hair cells.
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Specimen
3F bv/bv:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Srrm4bv/Srrm4bv
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
3F bv/bv
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Expression was detected in the inner hair cells and the outer hair cells. Note phenotype in inner hair cell row.
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Specimen
not shown bv/+:
postnatal day 5; Srrm4bv/Srrm4 +
(more )
Specimen
not shown bv/+:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Srrm4bv/Srrm4+
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
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Expression was detected in the inner hair cells. Data was presented in fig. S4 as cell counts.
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Specimen
not shown bv/bv:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Srrm4bv/Srrm4bv
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Age:
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postnatal day 5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
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Expression was detected in the inner hair cells, but the number of cells was decreased 71% in the mutant. Data was presented in fig. S4 as cell counts.
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Analysis Tools