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Gene Expression Data
Assay Details
Assay
Reference: J:203127 Hussain MS, et al., CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013 Dec 20;22(25):5199-214
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5636588
Gene symbol: Cdk6
Gene name: cyclin dependent kinase 6
Antibody: Anti-Cdk6 (ab54576)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Two antibodies were described MGI:5636509 and MGI:5636511; either could have been used in this assay.
Results
Specimen 8A: embryonic day 11.5 (more )
Note: Double labeled: red - Cdk6; green - Nes (assay MGI:5636589).
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 8A Merge , 8A Cdk6 Expression was detected in intermediate or basal progenitors in the developing neuroepithelium of the cerebral cortex.
Specimen 8B: embryonic day 15.5 (more )
Note: Double labeled: red - Cdk6; green - Nes (assay MGI:5636589).
Structure Level Pattern Image Note
TS23: cerebral cortex Present 8B Cdk6 , 8B Merge Expression was present in all the major sites of the developing neuroepithelium. Staining was prominent at the apical ventricular surface.
TS23: cerebral cortex subventricular zone Present 8B Merge , 8B Cdk6
Specimen 8C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present 8C Cdk6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory