Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Ctgf-cre)1Aibs
Name:	transgene insertion 1, Ed Lein
MGI ID:	MGI:5635429
Synonyms:	Ctgf-Tg1-Cre
Transgene:	Tg(Ctgf-cre)1Aibs  Location: unknown
Alliance:	Tg(Ctgf-cre)1Aibs page

Strain of Origin:

(C57BL/6 x C3H)F1 x C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Ctgf-cre)1Aibs expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Ccn2 (MGI:95537)   Mutation details: The 189 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-257E12, containing the entire Ctgf locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Ctgf locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex and hippocampus by the Ctgf promoter/enhancer regions within the BAC transgene. (J:146821)

Activity:	Tissue activity of this recombinase allele
Driver:	Ccn2 (mouse) Summary of all recombinase alleles driven by Ccn2. Alliance mouse Ccn2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:220523 Harris JA, et al., Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits. 2014;8:76
All:	2 reference(s)