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Gene Expression Data
Assay Details
Assay
Reference: J:220075 Unger EK, et al., Medial amygdalar aromatase neurons regulate aggression in both sexes. Cell Rep. 2015 Feb 3;10(4):453-62
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5634560
Gene symbol: Cyp19a1
Gene name: cytochrome P450, family 19, subfamily a, polypeptide 1
Reporter: lacZ
Antibody: anti-B-galactosidase (ab9361)
Detection system: Secondary antibody
Results
Specimen 2D left: postnatal adult; Cyp19a1tm1.1Shah/Cyp19a1+ (more )
Structure Level Pattern Image Note
TS28: medial amygdaloid nucleus Present Regionally restricted 2D Aro+/PIN Expression is detected in the posterodorsal medial amygdala.
Specimen 2D right: postnatal adult; Cyp19a1tm1.1Shah/Cyp19a1tm2.1(cre)Shah (more )
Structure Level Pattern Image Note
TS28: medial amygdaloid nucleus Absent 2D AroCre/PIN
TS28: brain Present Single cells 2D AroCre/PIN Expression is present in neurons not located in the posterodorsal medial amygdala.
Specimen S2A upper: postnatal adult; Cyp19a1tm1.1Shah/Cyp19a1+, Gad1tm1Tama/Gad1+ (more )
Note: Double labeled: red - Cyp19a1; green - Gad1 (assay MGI:5634580).
Structure Level Pattern Image Note
TS28: medial amygdaloid nucleus Present Regionally restricted S2A upper B-galactosidase , S2A upper Merge Expression is detected in the posterodorsal medial amygdala. Most (84%) of these neurons co-express a biosynthetic enzyme for the neurotransmitter GABA.
Specimen S2A lower: postnatal adult; Cyp19a1tm1.1Shah/Cyp19a1+, Gad1tm1Tama/Gad1+ (more )
Note: Double labeled: red - Cyp19a1; green - Gad1 (assay MGI:5634580).
Structure Level Pattern Image Note
TS28: medial amygdaloid nucleus Present Regionally restricted S2A lower Merge , S2A lower B-galactosidase Expression is detected in the posterodorsal medial amygdala. Most (91%) of these neurons co-express a biosynthetic enzyme for the neurotransmitter GABA.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory