About   Help   FAQ
Gad1tm1Tama
Targeted Allele Detail
Summary
Symbol: Gad1tm1Tama
Name: glutamate decarboxylase 1; targeted mutation 1, Nobuaki Tamamaki
MGI ID: MGI:3590300
Synonyms: GAD67-GFP, GAD67GFP
Gene: Gad1  Location: Chr2:70392109-70432358 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Alliance: Gad1tm1Tama page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86389
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn EGFP was inserted at the ATG in exon 1. A loxP-flanked neo was included in the vector. Western blot demonstrated that these mutants had less GFP in the cerebral cortex than when the neo was removed. (J:86389, J:144883)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:  64 strains or lines available
References
Original:  J:86389 Tamamaki N, et al., Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J Comp Neurol. 2003 Dec 1;467(1):60-79
All:  50 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/24/2024
MGI 6.24
The Jackson Laboratory