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Gene Expression Data
Assay Details
Assay
Reference: J:124527 Hatta T, et al., The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system. J Neurosci. 2002 Jul 1;22(13):5516-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5617749
Gene symbol: Il6st
Gene name: interleukin 6 signal transducer
Antibody: anti-human gp130 antibody
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: central nervous system Present 1a
TS19: dorsal root ganglion Present 1a
TS19: telencephalon Weak 1a Faint expression in the cerebral wall.

Specimen 1b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Moderate Widespread 1b Expressed throughout the cerebral wall, with some cells heavily stained.

Specimen 1c: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Strong 1c Cells and fibers were stained heavily.
TS23: cortical plate Strong 1c Cells and fibers were stained heavily.

Specimen 1d: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Strong 1d Expressed in cells and fibers.
TS26: cortical plate Strong 1d Expressed in cells and fibers.
TS26: cerebral cortex ventricular zone Present 1d Decreased staining intensity.

Specimen 1e: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Weak 1e Faint expression in the cerebral wall.

Specimen 1f: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Moderate Widespread 1f Expressed throughout the cerebral wall, with some cells heavily stained.
TS21: cerebral cortex intermediate zone Moderate Widespread 1f Moderate expression, with some cells heavily stained.
TS21: cerebral cortex ventricular layer Moderate Widespread 1f Moderate expression, with some cells heavily stained.
TS21: cortical preplate Moderate Widespread 1f Moderate expression, with some cells heavily stained.

Specimen 1g: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 1g Staining of the progenitor cells became more intense.
TS22: cortical plate Present 1g The number of heavily stained neurons increased.

Specimen 1h: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Strong 1h Cells and fibers were stained heavily.
TS23: cortical plate Strong 1h Cells and fibers were stained heavily.

Specimen 1i: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Strong Regionally restricted 1i Cells and fibers were stained heavily. Not expressed in the mitotic cells on the ventricular surface.

Specimen 1j: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Strong 1j Expressed in cells and fibers.
TS26: cerebral cortex ventricular zone Present 1j Decreased staining intensity.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory