Klf3 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:206507 Kelsey L, et al., ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. PLoS Genet. 2013;9(7):e1003612
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5617016
Gene symbol:	Klf3
Gene name:	Kruppel-like transcription factor 3 (basic)

Reporter:	lacZ
	Direct Detection

Results

10A ©

Specimen 10A: embryonic day 10.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Strong	Widespread	10A	Expressed at discrete but widespread sites.

10B ©

Specimen 10B: embryonic day 10.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS17: outflow tract	Strong		10B

10C ©

Specimen 10C: embryonic day 12.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Strong	Widespread	10C	Expressed discrete albeit widespread sites.

10D ©

Specimen 10D: embryonic day 12.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS20: outflow tract	Strong		10D

10E ©

Specimen 10E: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: heart atrium	Strong		10E
TS28: heart ventricle	Strong		10E

10F ©

Specimen 10F: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel	Present		10F	Including those of the skeletal muscle.

10G ©

Specimen 10G: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: atrium cardiac muscle	Present		10G
TS28: heart blood vessel	Strong		10G

10H ©

Specimen 10H: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: ventricle cardiac muscle	Present	Diffuse	10H	Expression was diffuse and punctate.

10I ©

Specimen 10I: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Image
TS28: aorta	Strong	10I
TS28: coronary artery	Strong	10I
TS28: heart valve	Strong	10I
TS28: pulmonary artery	Strong	10I

10J ©

Specimen 10J: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: aortic valve	Strong		10J

10K ©

Specimen 10K: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: aorta	Strong		10K
TS28: inferior vena cava	Strong		10K

10L ©

Specimen 10L: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel endothelium	Present		10L
TS28: blood vessel smooth muscle	Present		10L

Specimen not shown: embryonic day 10.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS17: cardiac muscle tissue	Present	Diffuse		Expression was diffuse and punctate.

Specimen not shown: embryonic day 12.5; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS20: cardiac muscle tissue	Present	Diffuse		Expression was diffuse and punctate.

S8A Atrium ©

Specimen S8A Atrium: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: atrium cardiac muscle	Present		S8A Atrium

Specimen S8A Atrio-ventricular valve: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: atrioventricular valve	Present		S8A Atrio-ventricular valve

Specimen S8A Left ventricle: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: heart left ventricle	Present		S8A Left ventricle
TS28: ventricle cardiac muscle	Present		S8A Left ventricle

S8A Aorta ©

Specimen S8A Aorta: postnatal adult; Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: aorta	Present		S8A Aorta

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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