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Gene Expression Data
Assay Details
Assay
Reference: J:206507 Kelsey L, et al., ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. PLoS Genet. 2013;9(7):e1003612
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5617016
Gene symbol: Klf3
Gene name: Kruppel-like transcription factor 3 (basic)
Reporter: lacZ
Direct Detection
Results
Specimen 10A: embryonic day 10.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS17: embryo Strong Widespread 10A Expressed at discrete but widespread sites.

Specimen 10B: embryonic day 10.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS17: outflow tract Strong 10B

Specimen 10C: embryonic day 12.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS20: embryo Strong Widespread 10C Expressed discrete albeit widespread sites.

Specimen 10D: embryonic day 12.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS20: outflow tract Strong 10D

Specimen 10E: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: heart atrium Strong 10E
TS28: heart ventricle Strong 10E

Specimen 10F: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: blood vessel Present 10F Including those of the skeletal muscle.

Specimen 10G: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: atrium cardiac muscle Present 10G
TS28: heart blood vessel Strong 10G

Specimen 10H: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: ventricle cardiac muscle Present Diffuse 10H Expression was diffuse and punctate.

Specimen 10I: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: aorta Strong 10I
TS28: coronary artery Strong 10I
TS28: heart valve Strong 10I
TS28: pulmonary artery Strong 10I

Specimen 10J: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: aortic valve Strong 10J

Specimen 10K: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: aorta Strong 10K
TS28: inferior vena cava Strong 10K

Specimen 10L: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 10L
TS28: blood vessel smooth muscle Present 10L

Specimen not shown: embryonic day 10.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present Diffuse Expression was diffuse and punctate.

Specimen not shown: embryonic day 12.5; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present Diffuse Expression was diffuse and punctate.

Specimen S8A Atrium: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: atrium cardiac muscle Present S8A Atrium

Specimen S8A Atrio-ventricular valve: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: atrioventricular valve Present S8A Atrio-ventricular valve

Specimen S8A Left ventricle: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: heart left ventricle Present S8A Left ventricle
TS28: ventricle cardiac muscle Present S8A Left ventricle

Specimen S8A Aorta: postnatal adult; Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (more )
Structure Level Pattern Image Note
TS28: aorta Present S8A Aorta


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory