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Gene Expression Data
Assay Details
Assay
Reference: J:174196 Heydeck W, et al., PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn. 2011 Aug;240(8):1938-48
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5586688
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 2E Expression is in the V3 interneurons and their progenitors immediately dorsal to the floor plate.
Specimen 2F: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent 2F
Specimen 2G: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 2G Expression is in the ventral midline.
Specimen 2H: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent 2H
Specimen 4E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 4E
Specimen 4F: embryonic day 9.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 4F There is an increase in expressing cells.
Specimen 4G: embryonic day 9.5; Vangl2Lp-m1Jus/Vangl2Lp-m1Jus (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 4G The expression domain is the same as in wild-type embryos.
Specimen 4H: embryonic day 9.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi, Vangl2Lp-m1Jus/Vangl2Lp-m1Jus (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 4H The expression domain is closer to the midline in this mutant.
Specimen 5I: embryonic day 10.5; Intutm1.2Aliu/Intu+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 5I Expression is in V3 interneurons.
Specimen 5J: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu, Vangl2Lp-m1Jus/Vangl2+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 5J The number of expressing cells is reduced.
Specimen 5K: embryonic day 10.5; Intutm1.2Aliu/Intu+, Vangl2Lp-m1Jus/Vangl2Lp-m1Jus (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 5K Expression in the mutant neural tube is the same as in wild-type.
Specimen 5L: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu, Vangl2Lp-m1Jus/Vangl2Lp-m1Jus (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 5L Expression is in the ventral midline.
Specimen 7E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 7E Expression is in the V3 interneurons and their progenitors immediately dorsal to the floor plate.
Specimen 7F: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 7F Expression is in the ventral midline.
Specimen 7G: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 7G Expression is in the ventral midline.
Specimen 7H: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 7H Expression is in the ventral midline.
Specimen S1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S1E Expression is in the V3 interneurons and their progenitors immediately dorsal to the floor plate.
Specimen S1F: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent S1F
Specimen S1G: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S1G Expression is in the ventral midline.
Specimen S1H: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent S1H
Specimen S3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S3E Expression is in the V3 interneurons and their progenitors immediately dorsal to the floor plate.
Specimen S3F: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S3F Expression is in the ventral midline.
Specimen S3G: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S3G Expression is in the ventral midline.
Specimen S3H: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S3H Expression is in the ventral midline.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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