Gli1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:181269 Hong M, et al., Neogenin regulates sonic hedgehog pathway activity during digit patterning. Dev Dyn. 2012 Mar;241(3):627-37
Assay type:	RNA in situ
MGI Accession ID:	MGI:5586509
Gene symbol:	Gli1
Gene name:	GLI-Kruppel family member GLI1

Probe:	Gli1 probe21
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen not shown Wt: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: hindlimb bud	Present

Specimen not shown Neo1Gt/Gt: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: hindlimb bud	Present			Expression in this mutant is the same as in wild-type embryos.

Specimen 2C Control: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	2C Gli1 Control

Specimen 2C Neo1Gt/Gt: embryonic day 11.5; Neo1^{Gt(KST265)Byg}/Neo1^{Gt(KST265)Byg} (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	2C Gli1 Neo1Gt/Gt	There is an additional ectopic expression domain at the anterior edge of the right hindlimb bud in two out of eight mutants examined.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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