About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:132939 Varadkar P, et al., Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells. Dev Dyn. 2008 Apr;237(4):1144-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5585610
Gene symbol: Notch2
Gene name: notch 2
Results
Specimen 2A: embryonic day 14.5 (more )
Note: Double labeled: green - Notch2; red - Acta2 (assay MGI:5585615).
Structure Level Pattern Image Note
TS22: dorsal aorta Present Regionally restricted 2C , 2A Expression is in smooth muscle cells.
TS22: pulmonary artery Present Regionally restricted 2C , 2A Expression is in smooth muscle cells.

Specimen 2D: embryonic day 14.5 (more )
Note: F: The merged picture is a higher magnification of the boxed region in E. Double labeled: green - Notch2; red - Pecam1 (assay MGI:5585612).
Structure Level Pattern Image Note
TS22: dorsal aorta Present Regionally restricted 2D , 2F Expression is in smooth muscle cells, absent in endothelial cells.

Specimen 2G: embryonic day 14.5 (more )
Note: Double labeled: green - Notch2; red - alpha-Actinin.
Structure Level Pattern Image Note
TS22: atrioventricular endocardial cushion Present Regionally restricted 2I , 2G Expression is in the mesenchyme.
TS22: pulmonary valve Present Regionally restricted 2I , 2G Expression is in the mesenchyme.
TS22: cardiac muscle tissue Weak 2G , 2I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory