Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Angpt1tm1.1Yona
Name:	angiopoietin 1; targeted mutation 1.1, Yoshikazu Nakaoka
MGI ID:	MGI:5585457
Synonyms:	Ang1fl, Ang1flox
Gene:	Angpt1  Location: Chr15:42288119-42540373 bp, - strand  Genetic Position: Chr15, 16.69 cM
Alliance:	Angpt1tm1.1Yona page

Germline Transmission:	Earliest citation of germline transmission: J:213456
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 1 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 1. (J:213456, J:288357)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angpt1 Mutation:	35 strains or lines available

Original:	J:213456 Lee J, et al., Angiopoietin-1 guides directional angiogenesis through integrin alphavbeta5 signaling for recovery of ischemic retinopathy. Sci Transl Med. 2013 Sep 18;5(203):203ra127
All:	10 reference(s)