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Gene Expression Data
Assay Details
Assay
Reference: J:111609 Anderson RM, et al., Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn. 2006 Aug 7;235(9):2507-2520
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5584015
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 6A
TS17: facial ganglion Present 6A
TS17: glossopharyngeal ganglion Present 6A
TS17: trigeminal ganglion Present 6A
TS17: vagus ganglion Present 6A
Specimen 6B: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: glossopharyngeal ganglion Present 6B The vagus (X) and glossopharyngeal (IX) plexuses are expanded, fused together, and generally disorganized in this mutant.
TS17: vagus ganglion Present 6B The vagus (X) and glossopharyngeal (IX) plexuses are expanded, fused together, and generally disorganized in this mutant.
TS17: acoustic ganglion Present 6B
TS17: facial ganglion Present 6B
TS17: trigeminal ganglion Present 6B
Specimen 6C: embryonic day 10.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 6C Expression is in a rudimentary portion of the trigeminal ganglion, the other cranial ganglia are absent in this mutant.
Specimen 6D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 6D
Specimen 6E: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 6E Expression is in disarrayed dorsal root ganglia.
Specimen 6F: embryonic day 10.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present Regionally restricted 6F Most dorsal root ganglia are absent in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory