Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Muc5btm1.2Evns
Name:	mucin 5, subtype B, tracheobronchial; targeted mutation 1.2, Christopher M Evans
MGI ID:	MGI:5576290
Synonyms:	Muc5bdelta
Gene:	Muc5b  Location: Chr7:141392807-141426821 bp, + strand  Genetic Position: Chr7, 87.29 cM, cytoband F5
Alliance:	Muc5btm1.2Evns page

Germline Transmission:	Earliest citation of germline transmission: J:207159
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed the floxed exon 1. Immunohistochemistry confirmed absence of protein in lungs. (J:207159)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Muc5b Mutation:	215 strains or lines available

Original:	J:207159 Roy MG, et al., Muc5b is required for airway defence. Nature. 2014 Jan 16;505(7483):412-6
All:	10 reference(s)