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Kif18atm1Zgwg
Targeted Allele Detail
Summary
Symbol: Kif18atm1Zgwg
Name: kinesin family member 18A; targeted mutation 1, Zhugang Wang
MGI ID: MGI:5575486
Gene: Kif18a  Location: Chr2:109111165-109172094 bp, + strand  Genetic Position: Chr2, 56.55 cM
Alliance: Kif18atm1Zgwg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211103
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced part of exon 2. Immunohistochemistry confirmed the absence of protein expression in testes. (J:211103)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif18a Mutation:  63 strains or lines available
References
Original:  J:211103 Liu XS, et al., Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E. Genes Cancer. 2010 Jan;1(1):26-39
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory