Gdf5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:156949 Perez WD, et al., Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development. Dev Dyn. 2010 Feb;239(2):446-57
Assay type:	RNA in situ
MGI Accession ID:	MGI:5572913
Gene symbol:	Gdf5
Gene name:	growth differentiation factor 5

Probe:	Gdf5 probe11
Probe preparation:	Antisense RNA

Results

5E ©

Specimen 5E: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: hand	Present	Regionally restricted	5E	Expression is in cells flanking the phalanx and metacarpal elements and in cells surrounding the developing carpal elements.

5F ©

Specimen 5F: embryonic day 13.5; Hoxa13^tm1.1Mrc/Hoxa13^tm1.1Mrc (more

)

Structure	Level	Pattern	Image
TS21: forelimb digit 2 metacarpus pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 2 phalanx pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 3 metacarpus pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 3 phalanx pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 4 metacarpus pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 4 phalanx pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 5 metacarpus pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 5 phalanx pre-cartilage condensation	Present	Diffuse	5F
TS21: carpus pre-cartilage condensation	Present	Diffuse	5F
TS21: forelimb digit 1 metacarpus pre-cartilage condensation	Trace	Diffuse	5F
TS21: forelimb digit 1 phalanx pre-cartilage condensation	Trace	Diffuse	5F

5G ©

Specimen 5G: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: future tarsus	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.
TS21: hindlimb digit 1	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.
TS21: hindlimb digit 2	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.
TS21: hindlimb digit 3	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.
TS21: hindlimb digit 4	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.
TS21: hindlimb digit 5	Strong	Regionally restricted	5G	Expression is in the phalanx, metatarsal, and tarsal joint fields.

5H ©

Specimen 5H: embryonic day 13.5; Hoxa13^tm1.1Mrc/Hoxa13^tm1.1Mrc (more

)

Structure	Level	Pattern	Image
TS21: future tarsus	Weak	Diffuse	5H
TS21: hindlimb digit 1	Weak	Diffuse	5H
TS21: hindlimb digit 2	Weak	Diffuse	5H
TS21: hindlimb digit 3	Weak	Diffuse	5H
TS21: hindlimb digit 4	Weak	Diffuse	5H
TS21: hindlimb digit 5	Weak	Diffuse	5H

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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