Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atp1a3tm1.1Kwk
Name:	ATPase, Na+/K+ transporting, alpha 3 polypeptide; targeted mutation 1.1, Kiyoshi Kawakami
MGI ID:	MGI:5572809
Gene:	Atp1a3  Location: Chr7:24677592-24705383 bp, - strand  Genetic Position: Chr7, 13.73 cM
Alliance:	Atp1a3tm1.1Kwk page

Germline Transmission:	Earliest citation of germline transmission: J:210870
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 6 were replaced with a loxP site, the cDNA fused to EGFP, an FRT-flanked neomycin resistance cassette, a loxP site and STOP/polyadenylation cassette. Cre-mediated recombination removed the fusion cDNA and selection cassette. (J:210870)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp1a3 Mutation:	68 strains or lines available

Original:	J:210870 Ikeda K, et al., Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice. J Physiol. 2013 Jul 1;591(Pt 13):3433-49
All:	4 reference(s)