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Gene Expression Data
Assay Details
Assay
Reference: J:156934 Santisteban P, et al., Dynamic expression of groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation. Dev Dyn. 2010 Jan 27;239(3):980-986
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5572015
Gene symbol: Tle1
Gene name: transducin-like enhancer of split 1
Antibody: anti-Grg1
Detection system: Secondary antibody
Results
Specimen S2 7-8S: embryonic day 8.5 (more )
Note: 7-8 somite pair stage
Structure Level Pattern Image Note
TS13: head Present S2_7-8S Grg1 Most of the staining was nonspecific/cytoplasmic, as seen by its failure to be blocked by peptide immunogen. Nuclear staining was observed in the head that was blocked by antigen.
TS13: embryo endoderm Absent S2_7-8S Grg1 No nuclear staining.
TS13: foregut-midgut junction endoderm Absent S2_7-8S Grg1 No nuclear staining.

Specimen S2 23S: embryonic day 9.5 (more )
Note: 23 somite pair stage
Structure Level Pattern Image Note
TS15: neural tube Present S2_23S Grg1 Nuclear staining.
TS15: embryo mesenchyme Present Regionally restricted S2_23S Grg1 Exoressed in dorsal mesenchyme.
TS15: cardiovascular system Present Regionally restricted S2_23S Grg1 Expresse in lateral endothelium.
TS15: embryo endoderm Absent S2_23S Grg1 No nuclear staining.
TS15: hepatic primordium Absent S2_23S Grg1 No nuclear staining.

Specimen not shown: embryonic day 8.0 (more )
Note: 3-4 somite pair stage
Structure Level Pattern Image Note
TS12: embryo endoderm Absent No nuclear staining.
TS12: foregut diverticulum endoderm Absent No nuclear staining.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory