Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd79atm3(cre/ERT2)Reth
Name:	CD79A antigen (immunoglobulin-associated alpha); targeted mutation 3, Michael Reth
MGI ID:	MGI:5568505
Synonyms:	mb1-CreERT2, MCE
Gene:	Cd79a  Location: Chr7:24596922-24601283 bp, + strand  Genetic Position: Chr7, 13.49 cM
Alliance:	Cd79atm3(cre/ERT2)Reth page

Germline Transmission:	Earliest citation of germline transmission: J:194830
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	BALB/c

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Cd79atm3(cre/ERT2)Reth expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Cd79a (MGI:101774)     A cDNA encoding the tamoxifen-inducible cre recombinase (cre/ERT2) was knocked into exon 2. (J:217519)

Activity:	Tissue activity of this recombinase allele
Driver:	Cd79a (mouse) Summary of all recombinase alleles driven by Cd79a. Alliance mouse Cd79a gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd79a Mutation:	22 strains or lines available

Original:	J:194830 Schweighoffer E, et al., The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway. Immunity. 2013 Mar 21;38(3):475-88
All:	10 reference(s)