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Gene Expression Data
Assay Details
Assay
Reference: J:136395 Zordan P, et al., Comparative analysis of proneural gene expression in the embryonic cerebellum. Dev Dyn. 2008 Jun;237(6):1726-35
Assay type: RNA in situ
MGI Accession ID: MGI:5561118
Gene symbol: Neurog1
Gene name: neurogenin 1
Probe: Ngn1 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen not shown: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: cerebellum primordium Absent
Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Present Regionally restricted 2C Expression was detected at the rostral end of the cerebellum.
Specimen 4B, A/B inlay, B/C inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Ptf1a (A/B; assay MGI:5562341) or Ascl1 (B/C; assay MGI:5560710).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 4B , 4A/B overlay , 4B/C overlay Expression was detected in ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen 4B', A'/B' inlay, B'/C' inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Ptf1a (A'/B'; assay MGI:5562341) or Ascl1 (B'/C'; assay MGI:5560710).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 4B' , 4A'/B' overlay , 4B'/C' overlay Expression was detected in the ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen 5A,A": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Neurog2 (assay MGI:5560711).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5A , 5A'' In anterior territories of the cerebellar ventricular zone, a high transcript level was detected in a domain located close to midline. Expression was weaker more laterally. There was overlap with Ngn2 (Neurog2) in posterior territories.
Specimen 5B,B": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Neurog2 (assay MGI:5560711).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5B'' , 5B In anterior territories of the cerebellar ventricular zone, a high transcript level was detected in a domain located close to midline. Expression was weaker more laterally. There was overlap with Ngn2 (Neurog2) in posterior territories.
Specimen 5C,C": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Neurog2 (assay MGI:5560711).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5C'' , 5C In anterior territories of the cerebellar ventricular zone, a high transcript level was detected in a domain located close to midline. Expression was weaker more laterally. There was overlap with Ngn2 (Neurog2) in posterior territories.
Specimen 5D,D": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; green - Neurog2 (assay MGI:5560711).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5D , 5D'' In anterior territories of the cerebellar ventricular zone, a high transcript level was detected in a domain located close to midline. Expression was weaker more laterally. There was overlap with Ngn2 (Neurog2) in posterior territories.
Specimen 6A, ovl: embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog1; red - Pax2 (assay MGI:5561119).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 6A Ngn1 , 6A ovl Expression was detected in the ventricular zone. There was a gap in the expression domain that coincided with the Pax2 domain in an adjacent section. More rostrally, expression was adjacent to a weaker Pax2 domain.
Specimen 7B, A/B inlay, B/C inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog1; red - Lhx1 (A/B; assay MGI:5562373) or Lhx5 (B/C; assay MGI:5562377).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 7A/B inlay , 7B , 7B/C inlay Expression was detected adjacent to and partially overlapping with the subventricular domains labeled by Lhx1 (A/B inlay) and Lhx5 (B/C inlay).
Specimen 8B, C inlay: embryonic day 13.5 (more )
Note: Fig. 8C Inlay - Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog1; blue - Pax2 (assay MGI:5561119); green - Ascl1 (assay MGI:5560710).
Structure Level Pattern Image Note
TS21: cerebellum ventricular layer Weak Regionally restricted 8C inlay , 8B Expression was detected in the ventricular zone. The anterior expression boundary was complementary to the Pax2 domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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