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Gene Expression Data
Assay Details
Assay
Reference: J:136395 Zordan P, et al., Comparative analysis of proneural gene expression in the embryonic cerebellum. Dev Dyn. 2008 Jun;237(6):1726-35
Assay type: RNA in situ
MGI Accession ID: MGI:5560711
Gene symbol: Neurog2
Gene name: neurogenin 2
Probe: Ngn2 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: cerebellum primordium Present Regionally restricted 1C Expression was detected in presumptive cerebellar nuclei progenitors.
Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Present Regionally restricted 3B Expression was detected in presumptive cerebellar nuclei neuronal precursors.
Specimen 3B': embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Present Regionally restricted 3B' Expression was detected in presumptive cerebellar nuclei neuronal precursors.
Specimen 3C Ngn2, ovl: embryonic day 11.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Hes5 (assay MGI:5561124).
Structure Level Pattern Image Note
TS19: cerebellum primordium Present Regionally restricted 3C Ngn2 , 3C ovl Expression was detected in presumptive cerebellar nuclei neuronal precursors that are located outside the Hes5 expression domain.
Specimen 4G, F/G inlay, G/H inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog2; green - Ptf1a (F/G; assay MGI:5562341) or Ascl1 (G/H; assay MGI:5560710).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 4G , 4G/H overlay , 4F/G overlay Expression was detected in the ventricular zone and occupied mostly the basal end of the ventricular neuroepithelium.
Specimen 4G', F'/G' inlay, G'/H' inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: red - Neurog2; green - Ptf1a (F'/G'; assay MGI:5562341) or Ascl1 (G'/H'; assay MGI:5560710).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 4G' , 4F'/G' overlay , 4G'/H' overlay Expression was detected in the ventricular zone and occupied mostly the basal end of the ventricular neuroepithelium.
Specimen 5A',A": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Neurog1 (assay MGI:5561118).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5A'' , 5A' In anterior territories of the cerebellar ventricular zone, expression was detected in the lateral ventricular zone. There was overlap with Ngn1 (Neurog1) in posterior territories.
Specimen 5B',B": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Neurog1 (assay MGI:5561118).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5B'' , 5B' In anterior territories of the cerebellar ventricular zone, expression was detected in the lateral ventricular zone. There was overlap with Ngn1 (Neurog1) in posterior territories.
Specimen 5C',C": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Neurog1 (assay MGI:5561118).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5C'' , 5C' In anterior territories of the cerebellar ventricular zone, expression was detected in the lateral ventricular zone. There was overlap with Ngn1 (Neurog1) in posterior territories.
Specimen 5D',D": embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Neurog1 (assay MGI:5561118).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5D' , 5D'' In anterior territories of the cerebellar ventricular zone, expression was detected in the lateral ventricular zone. There was overlap with Ngn1 (Neurog1) in posterior territories.
Specimen 6B, ovl: embryonic day 12.5 (more )
Note: ovl = overlay. Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Pax2 (assay MGI:5561119).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 6B Ngn2 , 6B ovl Expression was detected in the ventricular zone. Expression was adjacent to the Pax2 domain.
Specimen 7E, D/E inlay, E/F inlay: embryonic day 12.5 (more )
Note: Inlay - Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Lhx1 (D/E; assay MGI:5562373) or Lhx5 (E/F; assay MGI:5562377).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 7D/E inlay , 7E , 7E/F inlay Expression was detected in the ventricular zone adjacent to Lhx1 (D/E inlay) and Lhx5 (E/F inlay) in the subventricular zone.
Specimen 8F, F inlay: embryonic day 13.5 (more )
Note: Adjacent sections were pseudocolored and superimposed. Colors: green - Neurog2; red - Pax2 (assay MGI:5561119).
Structure Level Pattern Image Note
TS21: cerebellum ventricular layer Weak 8F inlay , 8F Expression was detected in the ventricular zone but was considerably down-regulated. The anterior boundary of expression was detectable underneath the Pax2 domain in the subventricular zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory