Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Cdkn2atm3Nki
Name:	cyclin dependent kinase inhibitor 2A; targeted mutation 3, The Netherlands Cancer Institute
MGI ID:	MGI:5560507
Synonyms:	Cdkn2a/Cdkn2btm3Nki
Gene:	Cdkn2a  Location: Chr4:89192710-89212856 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Alliance:	Cdkn2atm3Nki page

Germline Transmission:	Earliest citation of germline transmission: J:273283
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site with a neo cassette between Frt sites, was inserted 3' of exon 1 beta of Cdkn2a. The neo cassette was excised in vitro. (J:273283)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2a Mutation:	62 strains or lines available

Original:	J:273283 Krimpenfort P, et al., A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis. Nat Commun. 2019 Mar 29;10(1):1425
All:	1 reference(s)