Cdkn2btm3Nki
Targeted Allele Detail
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Symbol: |
Cdkn2btm3Nki |
Name: |
cyclin dependent kinase inhibitor 2B; targeted mutation 3, The Netherlands Cancer Institute |
MGI ID: |
MGI:5560509 |
Synonyms: |
Cdkn2a/Cdkn2btm3Nki |
Gene: |
Cdkn2b Location: Chr4:89224536-89229276 bp, - strand Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
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Alliance: |
Cdkn2btm3Nki page
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Germline Transmission: |
Earliest citation of germline transmission:
J:273283
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutations: |
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Insertion, Intragenic deletion
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Cdkn2b was replaced by Hyg followed 3' by loxP. This allele was generated in ES cells. (J:273283)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cdkn2b Mutation: |
7 strains or lines available
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Original: |
J:273283 Krimpenfort P, et al., A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis. Nat Commun. 2019 Mar 29;10(1):1425 |
All: |
1 reference(s) |
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