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Gene Expression Data
Assay Details
Assay
Reference: J:138805 Ikegawa M, et al., Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice. Dev Dyn. 2008 Sep;237(9):2506-17
Assay type: RNA in situ
MGI Accession ID: MGI:5560271
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe21
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted 5b Expression was homogeneous in intensity along the proximo-distal axis. Expression was detected in all chondroprogenitor cells.
Specimen 5c: embryonic day 11.5 (more )
Note: Double labeled: blue - Sox9; purple - Sfrp2 (assay MGI:5560270).
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted 5c Expression was homogeneous in intensity along the proximo-distal axis. Expression was detected in all chondroprogenitor cells. Expression was mutually exclusive with Sfrp2 in the perichondrium.
Specimen 6d WT FL: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb Present 6d WT FL
Specimen 6d Mutant FL: embryonic day 12.5; Sfrp2tm1Ktas/Sfrp2tm1Ktas (more )
Structure Level Pattern Image Note
TS20: forelimb Present 6d Mutant FL
Specimen 6d WT HL: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb Present 6d WT HL
Specimen 6d Mutant HL: embryonic day 12.5; Sfrp2tm1Ktas/Sfrp2tm1Ktas (more )
Structure Level Pattern Image Note
TS20: hindlimb Present 6d Mutant HL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory