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Gene Expression Data
Assay Details
Assay
Reference: J:118340 Wang C, et al., A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype. Dev Dyn. 2007 Mar;236(3):769-76
Assay type: RNA in situ
MGI Accession ID: MGI:5559196
Gene symbol: Hoxd12
Gene name: homeobox D12
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 6A Expression was detected in the posterior half of the limb bud.

Specimen 6B: embryonic day 10.5; Gli3tm1Blnw/Gli3tm1Blnw (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 6B The expression domain expanded into the anterior limb bud of the delta68/delta68 mutant. However, it wasn't as broad or intense as the ectopic expression of the Xt/Xt mutant.

Specimen 6C: embryonic day 10.5; Gli3tm1Blnw/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 6C The expression domain expanded into the anterior limb bud of the delta68/Xt mutant. However, it wasn't as broad or intense as the ectopic expression of the Xt/Xt mutant.

Specimen 6D: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 6D Ectopic expression in the anterior limb bud was observed in the Xt/Xt mutant. It was broader and more intense than in both the delta68/delta68 and the delta68/Xt mutants.

Specimen 6E: embryonic day 10.5; Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 6E Ectopic expression into the anterior limb bud was not observed in the Xt/+ limb.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory