Gene Expression Data
Assay Details
Assay
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Reference:
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J:118340
Wang C, et al., A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype. Dev Dyn. 2007 Mar;236(3):769-76
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5559196
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Gene symbol:
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Hoxd12
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Gene name:
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homeobox D12
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Results
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Specimen
6A:
embryonic day 10.5
(more )
Specimen
6A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS17: limb |
Present |
Regionally restricted |
6A
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Expression was detected in the posterior half of the limb bud.
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Specimen
6B:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Gli3tm1Blnw/Gli3tm1Blnw
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: limb |
Present |
Regionally restricted |
6B
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The expression domain expanded into the anterior limb bud of the delta68/delta68 mutant. However, it wasn't as broad or intense as the ectopic expression of the Xt/Xt mutant.
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Specimen
6C:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6
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Mutant Allele(s):
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Gli3tm1Blnw/Gli3Xt-J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: limb |
Present |
Regionally restricted |
6C
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The expression domain expanded into the anterior limb bud of the delta68/Xt mutant. However, it wasn't as broad or intense as the ectopic expression of the Xt/Xt mutant.
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Specimen
6D:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gli3Xt-J/Gli3Xt-J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: limb |
Present |
Regionally restricted |
6D
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Ectopic expression in the anterior limb bud was observed in the Xt/Xt mutant. It was broader and more intense than in both the delta68/delta68 and the delta68/Xt mutants.
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Specimen
6E:
embryonic day 10.5; Gli3Xt-J/Gli3 +
(more )
Specimen
6E:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gli3Xt-J/Gli3+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: limb |
Present |
Regionally restricted |
6E
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Ectopic expression into the anterior limb bud was not observed in the Xt/+ limb.
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