Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grm3tm1Vbn
Name:	glutamate receptor, metabotropic 3; targeted mutation 1, Valeria Bruno
MGI ID:	MGI:5558949
Gene:	Grm3  Location: Chr5:9535541-9775170 bp, - strand  Genetic Position: Chr5, 3.69 cM
Alliance:	Grm3tm1Vbn page

Germline Transmission:	Earliest citation of germline transmission: J:123686
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A lacZ gene and neomycin resistance cassette was inserted between exon 2 and 3. In situ hybridization confirmed the absence of transcript expression in the brain. (J:123686)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grm3 Mutation:	54 strains or lines available

Original:	J:123686 Corti C, et al., The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection. J Neurosci. 2007 Aug 1;27(31):8297-308
All:	5 reference(s)