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Tg(Cd19-Klf3)2Bii
Transgene Detail
Summary
Symbol: Tg(Cd19-Klf3)2Bii
Name: transgene insertion 2, Basel Institute for Immunology
MGI ID: MGI:5558908
Transgene: Tg(Cd19-Klf3)2Bii  Location: unknown  
Alliance: Tg(Cd19-Klf3)2Bii page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Cd19-Klf3)2Bii expresses 1 gene
 
Mutation detailsMouse Klf3 cDNA tagged with human c-myc at the N terminal end is driven by the mouse Cd19 promoter. Mulitple lines were generated, however, data is from lines 2 and 23, which had indistinguishable phenotypes. Line 2 carries two copies of the transgene. This is a representative record for both lines. (J:172846)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:172846 Turchinovich G, et al., Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). Blood. 2011 Apr 7;117(14):3780-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory