Gene Expression Data
Assay Details
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Assay
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Reference:
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J:116645
Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5553461
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Gene symbol:
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Nodal
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Gene name:
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nodal growth differentiation factor
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Probe:
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Nodal cDNA3
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Probe preparation:
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Antisense
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Assay notes:
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Data was shown in Table 4.
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Results
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Specimen
+/+ 0-2:
embryonic day 8.0
(more  )
Note: 0-2 somites.
Specimen
+/+ 0-2:
(close  )
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Genetic Background:
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either: 129S1/SvImJ or C3H/HeJ
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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0-2 somites.
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Specimen
+/+ 3-7:
embryonic day 8.0
(more )
Note: 3-7 somites.
Specimen
+/+ 3-7:
(close )
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Genetic Background:
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either: 129S1/SvImJ or C3H/HeJ
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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3-7 somites.
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Specimen
+/+ 8-10:
embryonic day 8.5
(more )
Note: 8-10 somites.
Specimen
+/+ 8-10:
(close )
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Genetic Background:
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either: 129S1/SvImJ or C3H/HeJ
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Age:
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embryonic day 8.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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8-10 somites.
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Specimen
md-nc/md-nc 0-2:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Mgrn1md-nc/Mgrn1md-nc
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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0-2 somites.
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Specimen
md-nc/md-nc 3-7:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Mgrn1md-nc/Mgrn1md-nc
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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3-7 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: node |
Present |
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100% showed normal expression.
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| TS12: lateral plate mesoderm |
Present |
Regionally restricted |
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100% showed asymmetric expression in the left lateral plate mesenchyme.
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Specimen
md-nc/md-nc 8-10 variant 1:
embryonic day 8.5; Mgrn1md-nc/ Mgrn1md-nc
(more )
Note: 8-10 somites.
Specimen
md-nc/md-nc 8-10 variant 1:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Mgrn1md-nc/Mgrn1md-nc
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Age:
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embryonic day 8.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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8-10 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: node |
Present |
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50% showed normal expression.
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| TS13: lateral plate mesoderm |
Present |
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50% showed asymmetric expression in the left lateral plate mesenchyme.
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Specimen
md-nc/md-nc 8-10 variant 2:
embryonic day 8.5; Mgrn1md-nc/ Mgrn1md-nc
(more )
Note: 8-10 somites.
Specimen
md-nc/md-nc 8-10 variant 2:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Mgrn1md-nc/Mgrn1md-nc
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Age:
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embryonic day 8.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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8-10 somites.
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Specimen
md-2J/md-2J 0-2:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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0-2 somites.
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Specimen
md-2J/md-2J 3-7 variant 1:
embryonic day 8.0; Mgrn1md-2J/ Mgrn1md-2J
(more )
Note: 3-7 somites.
Specimen
md-2J/md-2J 3-7 variant 1:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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3-7 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: node |
Present |
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91.7% showed normal expression.
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| TS12: lateral plate mesoderm |
Present |
Regionally restricted |
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91.7% showed normal left-side expression. 8.3% showed bilateral expression.
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Specimen
md-2J/md-2J 3-7 variant 2:
embryonic day 8.0; Mgrn1md-2J/ Mgrn1md-2J
(more )
Note: 3-7 somites.
Specimen
md-2J/md-2J 3-7 variant 2:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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3-7 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: node |
Absent |
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8.3% showed absent expression.
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Specimen
md-2J/md-2J 8-10 variant 1:
embryonic day 8.5; Mgrn1md-2J/ Mgrn1md-2J
(more )
Note: 8-10 somites.
Specimen
md-2J/md-2J 8-10 variant 1:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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8-10 somites.
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Specimen
md-2J/md-2J 8-10 variant 2:
embryonic day 8.5; Mgrn1md-2J/ Mgrn1md-2J
(more )
Note: 8-10 somites.
Specimen
md-2J/md-2J 8-10 variant 2:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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8-10 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: node |
Absent |
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58.3% showed absent expression.
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